Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670805 | 0.90 | FFAR4 (0.55) | RAB9ANPC1POLBCHRM5CHRM1 | |
| SCHEMBL27605521 | 0.84 | RAB9A (0.51) | RAB9ANPC1POLBCHRM5CHRM1 | |
| SCHEMBL5717704 | 0.84 | LMNA (0.56) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL81136 | 0.83 | FABP4 (0.58) | RAB9ANPC1POLBCHRM5CHRM1 | |
| SCHEMBL80222 | 0.83 | PRKCI (0.46) | RAB9ANPC1POLBCHRM5CHRM1 | |
| SCHEMBL2777357 | 0.83 | RAB9A (0.52) | RAB9ANPC1POLBCHRM5CHRM1 | |
| SCHEMBL5791799 | 0.83 | PRKCI (0.46) | RAB9ANPC1POLBCHRM5CHRM1 | |
| SCHEMBL18007683 | 0.82 | RAB9A (0.49) | RAB9ANPC1POLBCHRM5CHRM1 | |
| SCHEMBL1405119 | 0.82 | RAB9A (0.50) | RAB9ANPC1POLBCHRM5CHRM1 | |
| SCHEMBL14015076 | 0.80 | RAB9A (0.44) | RAB9ANPC1POLBCHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4739625-B2 | — | — | 2011-08-03 | — | — | JP | claimed |
| EP-1206467-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001014371-A1 | N-HETEROCYCLIC DERIVATIVES AS NOS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 2001-03-01 | — | — | WO | disclosed |