Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 4/20 | 0.35 |
| ▸ | MMP9 | P14780 | 4/20 | 0.35 |
| ▸ | MMP12 | P39900 | 4/20 | 0.35 |
| ▸ | MMP1 | P03956 | 3/20 | 0.35 |
| ▸ | MMP3 | P08254 | 3/20 | 0.35 |
| ▸ | MMP8 | P22894 | 3/20 | 0.35 |
| ▸ | MMP13 | P45452 | 3/20 | 0.35 |
| ▸ | MMP14 | P50281 | 3/20 | 0.35 |
| ▸ | MMP16 | P51512 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915249 | 0.96 | HTT (0.39) | HSD11B1ELANEPKMGAANPSR1 | |
| SCHEMBL12961576 | 0.96 | HSD11B1 (0.42) | HSD11B1ELANEPKMGAANPSR1 | |
| SCHEMBL13822218 | 0.94 | HSD11B1 (0.36) | HSD11B1ELANEPKMGAANPSR1 | |
| SCHEMBL16260250 | 0.92 | HTT (0.37) | HSD11B1ELANEPKMGAANPSR1 | |
| SCHEMBL22202018 | 0.88 | HTT (0.39) | HSD11B1ELANEPKMGAANPSR1 | |
| SCHEMBL13064047 | 0.88 | HTT (0.39) | HSD11B1ELANEPKMGAANPSR1 | |
| SCHEMBL13918652 | 0.87 | HTT (0.33) | HSD11B1ELANEPKMMMP2MMP9 | |
| SCHEMBL10709557 | 0.86 | PKM (0.50) | HSD11B1ELANEPKMGAANPSR1 | |
| SCHEMBL14364646 | 0.86 | HTT (0.40) | HSD11B1ELANEPKMGAANPSR1 | |
| SCHEMBL12015735 | 0.85 | HSD11B1 (0.43) | HSD11B1ELANEPKMGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858977-B1 | POLYPHENYLENE-POLY(ARYL ETHER SULFONE) BLENDS, ARTICLES AND METHOD | SOLVAY ADVANCED POLYMERS LLC (US) | 2009-06-10 | — | — | EP | disclosed |