Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 8/20 | 0.55 |
| ▸ | CNR2 | P34972 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.48 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13816273 | 0.88 | CNR2 (0.59) | CNR2RAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL14098981 | 0.83 | RAB9A (0.61) | MAPK14CNR2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL105864 | 0.82 | CNR2 (0.53) | MAPK14CNR2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL19651858 | 0.82 | CYP2D6 (0.57) | MAPK14CNR2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL24553266 | 0.82 | HRH3 (0.49) | MAPK14CNR2CYP2C9CYP3A4MAPK13 | |
| SCHEMBL22468509 | 0.81 | RAB9A (0.58) | MAPK14CNR2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL19651825 | 0.80 | KMT2A (0.56) | CNR2RAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL12941950 | 0.79 | RAB9A (0.56) | MAPK14CNR2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1911834 | 0.79 | NPC1 (0.69) | MAPK14CNR2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13122955 | 0.79 | TAS1R3 (0.57) | CNR2RAB9ANPC1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541383-B2 | Asthma and allergic inflammation modulators | AMGEN INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-20080085891-A1 | Asthma and allergic inflammation modulators | FU ZICE | 2008-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080085891-A1 | Asthma and allergic inflammation modulators | IL5, TSLP, CYSLTR2 | MAPK14 1544/4885CNR2 234/4885RAB9A 2089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.