SCHEMBL13824754

SCHEMBL13824754

COc1ccc(C(=O)/C=C/c2c(C)[nH]c3ccccc23)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 6/20 0.76
▸ MAPT P10636 6/20 0.76
▸ MEN1 O00255 5/20 0.76
▸ LMNA P02545 3/20 0.76
▸ ALDH1A1 P00352 2/20 0.76
▸ PSMD14 O00487 1/20 0.70
▸ L3MBTL1 Q9Y468 1/20 0.70
▸ PIKFYVE Q9Y2I7 1/20 0.65
▸ MAOB P27338 7/20 0.56
▸ HSPD1 P10809 1/20 0.56
▸ TNFRSF1A P19438 1/20 0.56
▸ HSPE1 P61604 1/20 0.56
▸ CYP1B1 Q16678 1/20 0.56
▸ PADI4 Q9UM07 2/20 0.54
▸ F3 P13726 1/20 0.52
▸ CYP3A4 P08684 2/20 0.52
▸ BCHE P06276 1/20 0.52
▸ NFKB1 P19838 1/20 0.52
▸ NFKB2 Q00653 1/20 0.52
▸ RELA Q04206 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13727053 1.00 KMT2A (0.76) KMT2AMAPTMEN1LMNAALDH1A1
SCHEMBL16200790 0.85 PIKFYVE (0.79) KMT2AMAPTMEN1LMNAALDH1A1
SCHEMBL13723525 0.82 MAPT (1.00) KMT2AMAPTMEN1LMNAALDH1A1
SCHEMBL13723527 0.82 MAPT (1.00) KMT2AMAPTMEN1LMNAALDH1A1
SCHEMBL7832814 0.82 MAPT (0.67) KMT2AMAPTMEN1LMNAALDH1A1
SCHEMBL7832810 0.82 MAPT (0.67) KMT2AMAPTMEN1LMNAALDH1A1
SCHEMBL13723990 0.79 PIKFYVE (1.00) KMT2AMAPTMEN1LMNAALDH1A1
SCHEMBL30090615 0.79 PIKFYVE (1.00) KMT2AMAPTMEN1LMNAALDH1A1
SCHEMBL30591068 0.79 PIKFYVE (1.00) KMT2AMAPTMEN1LMNAALDH1A1
SCHEMBL13723992 0.79 PIKFYVE (1.00) KMT2AMAPTMEN1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10098352-B2 Honeybee repellents and uses thereof INSCENT, INC. (US) 2018-10-16 — — US claimed
US-11963527-B2 Compounds, compositions, and methods for altering insect and organism behavior BASF CORPORATION (US) 2024-04-23 — — US disclosed
US-20190104732-A1 Compounds, Compositions, and Methods for Altering Insect and Organism Behavior BASF CORPORATION 2019-04-11 — — US disclosed
US-10098352-B2 Honeybee repellents and uses thereof INSCENT, INC. (US) 2018-10-16 — — US disclosed
US-20160330960-A1 Honeybee Repellents and Uses Thereof INSCENT, INC. (US) 2016-11-17 — — US disclosed
US-20160330960-A1 Honeybee Repellents and Uses Thereof INSCENT, INC. (US) 2016-11-17 — — US disclosed
US-9439434-B2 Honeybee repellents and uses thereof INSCENT, INC. (US) 2016-09-13 — — US disclosed
US-9439434-B2 Honeybee repellents and uses thereof INSCENT, INC. (US) 2016-09-13 — — US disclosed
EP-2704578-B1 USE OF HONEYBEE REPELLENTS INSCENT INC (US) 2016-08-31 — — EP disclosed
EP-2704578-B1 USE OF HONEYBEE REPELLENTS INSCENT INC (US) 2016-08-31 — — EP disclosed
US-20160029628-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR REPELLING AN INSECT FROM AN AREA,ARTICLE, AND/OR STRUCTURE BAYER CROPSCIENCE LP (US) 2016-02-04 — — US disclosed
US-20150257384-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR ALTERING INSECT AND ORGANISM BEHAVIOR BASF CORPORATION 2015-09-17 — — US disclosed
US-20140155261-A1 Honeybee Repellents and Uses Thereof INSCENT, INC. (US) 2014-06-05 — — US disclosed
US-20140155261-A1 Honeybee Repellents and Uses Thereof INSCENT, INC. (US) 2014-06-05 — — US disclosed
WO-2012151556-A2 IMPROVED HONEYBEE REPELLENTS AND USES THEREOF INSCENT, INC. (US) 2012-11-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160029628-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR REPELLING AN INSECT FROM AN AREA,ARTICLE, AND/OR STRUCTURE ACHE, BCHE, SGMS1 KMT2A 1629/4885MAPT 830/4885MEN1 592/4885
US-20160330960-A1 Honeybee Repellents and Uses Thereof ACHE, AHNAK, L3MBTL3 KMT2A 794/4885MAPT 1877/4885MEN1 2382/4885
US-10098352-B2 Honeybee repellents and uses thereof ACHE, AHNAK, L3MBTL3 KMT2A 794/4885MAPT 1877/4885MEN1 2382/4885
US-11963527-B2 Compounds, compositions, and methods for altering insect and organism behavior ACHE, DDT, MGLL KMT2A 1063/4885MAPT 1884/4885MEN1 389/4885
US-20150257384-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR ALTERING INSECT AND ORGANISM BEHAVIOR ACHE, DDT, MGLL KMT2A 1063/4885MAPT 1884/4885MEN1 389/4885
US-20140155261-A1 Honeybee Repellents and Uses Thereof ACHE, AHNAK, L3MBTL3 KMT2A 794/4885MAPT 1877/4885MEN1 2382/4885
US-20190104732-A1 Compounds, Compositions, and Methods for Altering Insect and Organism Behavior ACHE, DDT, MGLL KMT2A 1063/4885MAPT 1884/4885MEN1 389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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