Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TNKS | O95271 | 8/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | EZH2 | Q15910 | 4/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13726386 | 0.74 | ALDH1A1 (0.50) | KDM4EGAAKMT2ASMN1; SMN2CNR1 | |
| SCHEMBL13725819 | 0.73 | LMNA (0.47) | KDM4ECNR2 | |
| SCHEMBL13725930 | 0.71 | TSHR (0.45) | KDM4EGAAKMT2ASMN1; SMN2MAPT | |
| SCHEMBL13725991 | 0.68 | FGFR1 (0.46) | KDM4EGAAKMT2ASMN1; SMN2 | |
| SCHEMBL13009455 | 0.68 | ALDH1A1 (0.37) | KDM4EGAAKMT2ASMN1; SMN2MAPT | |
| SCHEMBL13725548 | 0.68 | TSHR (0.48) | KDM4EKMT2ACNR2 | |
| SCHEMBL13725810 | 0.68 | CACNA1D (0.44) | KDM4EGAASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL13726073 | 0.67 | PTGES (0.46) | KDM4EGAAKMT2ASMN1; SMN2 | |
| SCHEMBL12516236 | 0.67 | KMT2A (0.39) | KDM4EGAAKMT2ASMN1; SMN2MAPT | |
| SCHEMBL17117549 | 0.67 | SCN1A (0.40) | KDM4EGAAKMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160362535-A1 | 5H-FURAN-2-ONE DERIVATIVES STABILIZATION OF ORGANIC MATERIAL | BASF SCHWEIZ AG (CH) | 2016-12-15 | — | — | US | disclosed |
| US-9458380-B2 | 5H-furan-2-one derivatives for stabilization of organic material | BASF SE (DE) | 2016-10-04 | — | — | US | disclosed |
| EP-2705082-B1 | 5H-FURAN-2-ONE DERIVATIVES FOR STABILIZATION OF ORGANIC MATERIAL | BASF SE (DE) | 2015-09-23 | — | — | EP | disclosed |
| US-20140058021-A1 | 5H-Furan-2-one Derivatives for Stabilization of Organic Material | BASF SE (DE) | 2014-02-27 | — | — | US | disclosed |
| WO-2012150527-A1 | 5H-FURAN-2-ONE DERIVATIVES FOR STABILIZATION OF ORGANIC MATERIAL | BASF SE (DE) | 2012-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160362535-A1 | 5H-FURAN-2-ONE DERIVATIVES STABILIZATION OF ORGANIC MATERIAL | C5, C9, CBR1 | KDM4E 3320/4885GAA 4653/4885KMT2A 3534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.