Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.39 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.38 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.38 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.38 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15314324 | 0.86 | TAAR1 (0.50) | TAAR1HTR2APOLBCTDSP1IDO1 | |
| SCHEMBL14048731 | 0.78 | ALDH1A1 (0.35) | HTR2ATDP1HTR3A | |
| SCHEMBL13825066 | 0.78 | CYP1A2 (0.46) | TAAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5238701 | 0.78 | TAAR1 (0.62) | TAAR1HTR2AHMOX1PLAAT3PLAAT5 | |
| SCHEMBL7904900 | 0.78 | TAAR1 (0.62) | TAAR1HTR2AHMOX1HSP90AA1SIGMAR1 | |
| SCHEMBL3465495 | 0.77 | HTR3A (0.57) | HTR2ASIGMAR1HDAC3TDP1IDO1 | |
| SCHEMBL15583726 | 0.76 | TAAR1 (0.59) | TAAR1HTR2AHMOX1HSP90AA1SIGMAR1 | |
| SCHEMBL134452 | 0.76 | TAAR1 (0.59) | TAAR1HTR2AHMOX1HSP90AA1SIGMAR1 | |
| SCHEMBL30096319 | 0.76 | TAAR1 (0.59) | TAAR1HTR2AHMOX1HSP90AA1SIGMAR1 | |
| SCHEMBL16212624 | 0.75 | TAAR1 (0.43) | TAAR1HTR2AHMOX1PLAAT3PLAAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012150220-A1 | RADIOLABELED AMINO ACIDS FOR DIAGNOSTIC IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-11-08 | — | — | WO | disclosed |