Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | PDE6D | O43924 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.39 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.39 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.39 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10102840 | 0.96 | THRB (0.63) | THRBFFAR1FFAR4PDE6DTHRA | |
| SCHEMBL9915746 | 0.96 | THRB (0.63) | THRBFFAR1FFAR4PDE6DTHRA | |
| SCHEMBL9915750 | 0.92 | THRB (0.47) | THRBNR3C1SRD5A2TGM2PDE6D | |
| SCHEMBL9915747 | 0.91 | THRB (0.57) | THRBFFAR1PDE6DTHRAMMP12 | |
| SCHEMBL4402214 | 0.90 | TGM2 (0.49) | THRBNR3C1SRD5A2LTA4HTGM2 | |
| SCHEMBL11987133 | 0.90 | THRB (0.71) | THRBPDE6DTHRA | |
| SCHEMBL12933812 | 0.90 | THRB (0.59) | THRBFFAR1FFAR4PDE6DTHRA | |
| SCHEMBL9915807 | 0.89 | TGM2 (0.50) | THRBNR3C1SRD5A2LTA4HTGM2 | |
| SCHEMBL13777578 | 0.87 | THRB (0.55) | THRBSRD5A2LTA4HPDE6DTHRA | |
| SCHEMBL11938786 | 0.87 | THRB (0.55) | THRBNR3C1LTA4HPDE6DTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090148180-A1 | IMAGE BEARING MEMBER, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS AND METHOD OF FORMING IMAGE BEARING MEMBER | RICOH COMPANY, LTD. (JP) | 2009-06-11 | — | — | US | disclosed |