Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 12/20 | 0.66 |
| ▸ | PDCD1 | Q15116 | 8/20 | 0.66 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30828918 | 0.86 | PDCD1 (0.70) | CD274PDCD1S1PR1S1PR3PTGS2 | |
| SCHEMBL22401073 | 0.86 | PDCD1 (0.70) | CD274PDCD1S1PR1S1PR3PTGS2 | |
| SCHEMBL13726819 | 0.82 | NR4A2 (0.43) | CD274PDCD1CTSAHTR1AHTR7 | |
| SCHEMBL30609912 | 0.82 | NR4A2 (0.43) | CD274PDCD1CTSAHTR1AHTR7 | |
| SCHEMBL29558512 | 0.80 | CD274 (1.00) | CD274PDCD1EPHX1PTGS1 | |
| SCHEMBL358303 | 0.80 | CD274 (1.00) | CD274PDCD1EPHX1PTGS1 | |
| SCHEMBL16245269 | 0.79 | PDCD1 (0.76) | CD274PDCD1S1PR1S1PR3EPHX1 | |
| SCHEMBL18367730 | 0.75 | CD274 (0.70) | CD274PDCD1S1PR1S1PR3EPHX1 | |
| SCHEMBL30694686 | 0.75 | CD274 (0.65) | CD274PDCD1DHODH | |
| SCHEMBL21359619 | 0.72 | CD274 (0.55) | CD274PDCD1S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012150205-A1 | NOVEL SUBSTITUTED BENZYL ALCOHOL ESTERS OF CYCLOPROPANECARBOXYLIC ACID AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2012-11-08 | — | — | WO | disclosed |