Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RBP4 | P02753 | 2/20 | 0.36 |
| ▸ | CFTR | P13569 | 4/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 3/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5167760 | 0.85 | CFTR (0.53) | RECQLRBP4CFTRLDHANOTUM | |
| SCHEMBL5166126 | 0.81 | SMN1; SMN2 (0.39) | ALDH1A1GLAGAAMEN1KMT2A | |
| SCHEMBL13825597 | 0.75 | CFTR (0.38) | RECQLCFTRF10 | |
| SCHEMBL3349831 | 0.68 | ALDH1A1 (0.36) | RECQLKDM4EALDH1A1GAAHPGD | |
| SCHEMBL4690430 | 0.68 | F10 (0.47) | F10MEN1KMT2A | |
| SCHEMBL5627921 | 0.65 | ALDH1A1 (0.51) | CFTRF10GABRA1GABRG2GABRB3 | |
| SCHEMBL12038157 | 0.65 | CFTR (0.39) | RECQLCFTRNOTUMKDM4EALDH1A1 | |
| SCHEMBL45490 | 0.65 | LMNA (0.59) | RBP4CFTRNOTUMKDM4EALDH1A1 | |
| SCHEMBL8610066 | 0.64 | GRIA1 (0.52) | RBP4LDHALMNA | |
| SCHEMBL5165307 | 0.64 | CA12 (0.39) | RBP4CFTRNOTUMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773788-B1 | Quinazoline derivatives | NOVARTIS AG (CH) | 2012-11-14 | — | — | EP | disclosed |