SCHEMBL45490

SCHEMBL45490

COC(=O)c1ccccc1C(F)(F)F

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.59
GAA P10253 1/20 0.59
TSHR P16473 1/20 0.55
CFTR P13569 3/20 0.53
ALDH1A1 P00352 1/20 0.53
HSD17B10 Q99714 1/20 0.53
KDM4E B2RXH2 1/20 0.52
POLB P06746 1/20 0.52
ATM Q13315 1/20 0.52
RBP4 P02753 1/20 0.49
SLC6A4 P31645 1/20 0.49
SLC6A3 Q01959 1/20 0.49
ABL1 P00519 1/20 0.48
SRC P12931 1/20 0.48
PDK2 Q15119 1/20 0.48
NOTUM Q6P988 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA5A P35218 1/20 0.47
CA9 Q16790 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8550322 0.90 LMNA (0.50) LMNAGAATSHRCFTRALDH1A1
SCHEMBL10519876 0.84 LMNA (0.58) LMNAGAA
SCHEMBL1405144 0.84 LMNA (0.58) LMNAGAA
SCHEMBL5239843 0.84 CTSS (0.51) LMNAGAATSHRCFTRALDH1A1
SCHEMBL726068 0.84 TAS2R14 (0.54) LMNAGAATSHRCFTRALDH1A1
SCHEMBL1508457 0.84 LMNA (0.50) LMNAGAATSHRCFTRALDH1A1
SCHEMBL11074677 0.82 LMNA (0.56) LMNAGAA
SCHEMBL27570825 0.82 LMNA (0.56) LMNAGAA
SCHEMBL1788233 0.82 TSHR (0.57) LMNAGAATSHRCFTRALDH1A1
SCHEMBL10391427 0.82 LMNA (0.45) LMNAGAATSHRCFTRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120020114-A Preparation method of N-alkenyl amide compound 中国石油化工股份有限公司 2025-05-20 CN claimed
CN-120020115-A Process for the preparation of N- (alkyl-2-hydroxy) alkylamides and N-alkenylamides 中国石油化工股份有限公司 2025-05-20 CN claimed
CN-118946995-A Mixed additive, electrolyte for sodium secondary battery, battery module, battery pack, and electricity device 宁德时代新能源科技股份有限公司 2024-11-12 CN claimed
WO-2024086987-A1 MIXED ADDITIVE, ELECTROLYTE SOLUTION FOR SODIUM SECONDARY BATTERY, SODIUM SECONDARY BATTERY, BATTERY MODULE, BATTERY PACK, AND ELECTRIC DEVICE 宁德时代新能源科技股份有限公司 2024-05-02 WO claimed
CN-117913360-A Battery electrolyte and application thereof 香河昆仑新能源材料股份有限公司 2024-04-19 CN claimed
CN-117806124-A Positive photosensitive polyimide resin composition 万华化学集团股份有限公司 2024-04-02 CN claimed
CN-117510528-A Difluoro cyclic lithium sulfate borate salt, electrolyte containing difluoro cyclic lithium sulfate borate salt and lithium ion battery 香河昆仑新能源材料股份有限公司 2024-02-06 CN claimed
CN-117510530-A Annular lithium trioxyhexafluoroborate salt, electrolyte containing same and lithium ion battery 香河昆仑新能源材料股份有限公司 2024-02-06 CN claimed
CN-117510527-A Difluoromethylene cyclic disulfonic acid lithium borate salt, electrolyte containing same and lithium ion battery 香河昆仑新能源材料股份有限公司 2024-02-06 CN claimed
CN-117039172-A Lithium fluorocarboxylate sodium salt electrolyte 广东佳信新材料科技有限公司 2023-11-10 CN claimed
CN-107162995-A The synthetic method of isoxaflutole 无锡市稼宝药业有限公司 2017-09-15 CN claimed
CN-106565734-A Psoralen ester derivatives and applications thereof 中国科学院新疆理化技术研究所 2017-04-19 CN claimed
US-20170012208-A1 ORGANIC SEMICONDUCTOR FORMULATIONS USINVEST LLC 2017-01-12 US claimed
CN-105552440-A Lithium ion battery electrolyte for improving lithium battery pole piece interface DONGGUAN SHANSHAN BATTERY MAT CO LTD 2016-05-04 CN claimed
US-20150322094-A1 USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2015-11-12 US claimed
EP-2892343-A1 USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS Bayer CropScience AG (DE) 2015-07-15 EP claimed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
WO-2014037349-A1 USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2014-03-13 WO claimed
CN-101056628-A Ester derivatives and medicinal use thereof JAPAN TOBACCO INC (JP) 2007-10-17 CN claimed
WO-2005005382-A2 COMPOUNDS, COMPOSITIONS AND METHODS CYTOKINETICS, INC. (US) 2005-01-20 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150322094-A1 USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS CAT, HSF1, HPD LMNA 4642/4885GAA 170/4885TSHR 4556/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.