Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.50 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20145712 | 0.81 | MAPT (0.50) | LMNAMAPTALDH1A1CYP2C9SMN1; SMN2 | |
| SCHEMBL2843852 | 0.80 | TDP1 (0.55) | TDP1GLAHDAC3HDAC4HDAC1 | |
| SCHEMBL22524298 | 0.79 | APP (0.47) | LMNAMAPTALDH1A1SMN1; SMN2MAOB | |
| SCHEMBL20808077 | 0.78 | SMN1; SMN2 (0.53) | TDP1GLAHDAC3HDAC4HDAC1 | |
| SCHEMBL489257 | 0.77 | GLA (0.61) | TDP1GLAHDAC3HDAC4HDAC1 | |
| SCHEMBL11185426 | 0.77 | GLA (0.61) | TDP1GLAHDAC3HDAC4HDAC1 | |
| SCHEMBL10470695 | 0.77 | TDP1 (0.50) | TDP1GLAHDAC3HDAC4HDAC1 | |
| SCHEMBL13177035 | 0.77 | ALDH1A1 (0.51) | TDP1GLAHDAC3HDAC4HDAC1 | |
| SCHEMBL10470696 | 0.77 | TDP1 (0.50) | TDP1GLAHDAC3HDAC4HDAC1 | |
| SCHEMBL975354 | 0.77 | HDAC2 (0.70) | TDP1GLAHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4006035-A1 | QUINAZOLINE DERIVATIVES AS TYROSINE KINASE INHIBITORS FOR THE TREATMENT OF CANCER | Neupharma, Inc. (US) | 2022-06-01 | — | — | EP | disclosed |
| EP-1860098-B1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2012-11-14 | — | — | EP | disclosed |