Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.48 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10470695 | 1.00 | TDP1 (0.50) | TDP1GLAMAPTALDH1A1GAA | |
| SCHEMBL3073560 | 0.83 | HDAC2 (0.57) | TDP1GLAMAPTALDH1A1GAA | |
| SCHEMBL4684531 | 0.78 | MMP1 (0.61) | MAPTALDH1A1GAAHTTHDAC3 | |
| SCHEMBL4684535 | 0.78 | MMP1 (0.61) | MAPTALDH1A1GAAHTTHDAC3 | |
| SCHEMBL13825834 | 0.77 | TDP1 (0.52) | TDP1GLAMAPTALDH1A1HDAC3 | |
| SCHEMBL31326778 | 0.76 | GLA (0.61) | TDP1GLAMAPTALDH1A1GAA | |
| SCHEMBL8036556 | 0.75 | ALDH1A1 (0.51) | TDP1GLAMAPTALDH1A1GAA | |
| SCHEMBL13170487 | 0.75 | ALDH1A1 (0.51) | TDP1GLAMAPTALDH1A1GAA | |
| SCHEMBL975354 | 0.75 | HDAC2 (0.70) | TDP1GLAMAPTALDH1A1HTT | |
| Benzene SCHEMBL28260359 | 0.75 | HDAC2 (0.70) | TDP1GLAMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4963275-A | POLYOLEFIN MODIFIED BY AN UNSATURATED ANHYDRIDE, THE REACTION PRODUCT OF A POLYAMINE AND ACRYLIC COMPOUND AND A LACTONE OR POLYLACTONE; OIL ADDITIVES | EXXON CHEMICAL PATENTS INC. (US) | 1990-10-16 | — | — | US | disclosed |