Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 11/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19017855 | 0.86 | PTGDR2 (0.52) | KDM4EPTGDR2ALDH1A1KMT2AMEN1 | |
| SCHEMBL19017856 | 0.83 | KDM4E (0.45) | KDM4EPTGDR2ALDH1A1KMT2AMEN1 | |
| SCHEMBL13826525 | 0.81 | DPP4 (0.44) | KDM4EPTGDR2ALDH1A1KMT2AMEN1 | |
| SCHEMBL19017857 | 0.81 | PTGDR2 (0.44) | KDM4EPTGDR2ALDH1A1KMT2AMEN1 | |
| SCHEMBL19906092 | 0.80 | PTGDR2 (0.48) | KDM4EPTGDR2ALDH1A1KMT2AMEN1 | |
| SCHEMBL19906252 | 0.80 | PTGDR2 (0.39) | KDM4EPTGDR2ALDH1A1KMT2AMEN1 | |
| SCHEMBL19906097 | 0.79 | KDM4E (0.41) | KDM4EPTGDR2ALDH1A1KMT2AMEN1 | |
| SCHEMBL19906212 | 0.78 | KDM4E (0.38) | KDM4EPTGDR2ALDH1A1KMT2AMEN1 | |
| SCHEMBL19906074 | 0.78 | KDM4E (0.38) | KDM4EPTGDR2ALDH1A1KMT2AMEN1 | |
| SCHEMBL19017872 | 0.78 | KDM4E (0.40) | KDM4EPTGDR2ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012145728-A1 | BENZOTHIAZOLE COMPOUNDS AND THEIR PHARMACEUTICAL USE | GILEAD SCIENCES, INC. (US) | 2012-10-26 | — | — | WO | disclosed |