Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 3/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.61 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.46 |
| ▸ | TUBB | P07437 | 2/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12470090 | 0.75 | ALDH1A1 (0.57) | KDM4EALDH1A1HPGDTP53ERN1 | |
| SCHEMBL4601799 | 0.74 | ERN1 (0.65) | KDM4EALDH1A1HPGDHSD17B2TUBB4A | |
| SCHEMBL71536 | 0.73 | RAB9A (0.66) | KDM4EALDH1A1HPGDHSD17B2TP53 | |
| SCHEMBL13701209 | 0.72 | HTT (0.67) | PDE7APDE3APDE4BPDE4DPDE7B | |
| SCHEMBL19051349 | 0.72 | RAB9A (0.53) | KDM4EALDH1A1HPGDHSD17B2TP53 | |
| SCHEMBL10471050 | 0.72 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDTP53ERN1 | |
| SCHEMBL14610869 | 0.71 | ERN1 (0.65) | KDM4EALDH1A1HPGDHSD17B2TUBB4A | |
| SCHEMBL2491378 | 0.70 | RAB9A (0.72) | KDM4EALDH1A1HPGDHSD17B2TP53 | |
| SCHEMBL18832307 | 0.70 | HDAC6 (0.64) | KDM4EALDH1A1HPGDHSD17B2TP53 | |
| SCHEMBL12474107 | 0.70 | HSD17B1 (0.77) | HSD17B2HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012150369-A1 | PHOSPHODIESTERASE-7-INHIBITING HETEROCYCLIC DERIVATIVES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (ES) | 2012-11-08 | — | — | WO | disclosed |