⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL7957046 | 0.97 | — | — | |
| SCHEMBL89524 | 0.76 | — | — | |
| SCHEMBL1092516 | 0.70 | — | — | |
| SCHEMBL3186703 | 0.69 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL3345980 | 0.69 | RAB9A (0.47) | — | |
| SCHEMBL19710210 | 0.69 | — | — | |
| SCHEMBL13938473 | 0.67 | NPC1 (0.46) | — | |
| SCHEMBL11035016 | 0.66 | SMN1; SMN2 (0.68) | — | |
| SCHEMBL10846920 | 0.66 | LMNA (0.41) | — | |
| SCHEMBL9451948 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115057820-A | Method for synthesizing 4,5-dihydro-6-methylpyridazin-3(2H) -one from levulinic acid | 东莞理工学院 | 2022-09-16 | — | — | CN | claimed |
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| US-4255571-A | Catalytic dehydrogenation preparation of 3-pyridazones | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-03-10 | — | — | US | claimed |
| CN-115894324-B | Method for preparing pyrrolidone compound | 华北电力大学 | 2024-08-27 | — | — | CN | disclosed |
| CN-115894324-B | Method for preparing pyrrolidone compound | 华北电力大学 | 2024-08-27 | — | — | CN | disclosed |
| US-20230242535-A1 | IMIDAZOTHIADIAZOLE AND IMIDAZOPYRAZINE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR 4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION | BRISTOL MYERS SQUIBB CO (US) | 2023-08-03 | — | — | US | disclosed |
| US-20230242535-A1 | IMIDAZOTHIADIAZOLE AND IMIDAZOPYRAZINE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR 4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION | BRISTOL MYERS SQUIBB CO (US) | 2023-08-03 | — | — | US | disclosed |
| CN-115894324-A | Method for preparing pyrrolidone compound | 华北电力大学 | 2023-04-04 | — | — | CN | disclosed |
| CN-115894324-A | Method for preparing pyrrolidone compound | 华北电力大学 | 2023-04-04 | — | — | CN | disclosed |
| US-20230056447-A1 | TYK2 INHIBITORS AND USES THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-02-23 | — | — | US | disclosed |
| CN-115057820-A | Method for synthesizing 4,5-dihydro-6-methylpyridazin-3(2H) -one from levulinic acid | 东莞理工学院 | 2022-09-16 | — | — | CN | disclosed |
| EP-0208431-B1 | FUNGICIDAL PYRIDAZINES | ELI LILLY AND COMPANY (US) | 1990-07-11 | — | — | EP | disclosed |
| US-4791110-A | FOR PHYCOMYCETES ON PLANTS | ELI LILLY AND COMPANY (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0208431-A1 | Fungicidal pyridazines | ELI LILLY AND COMPANY (US) | 1987-01-14 | — | — | EP | disclosed |
| US-4595521-A | In liquid crystalline carrier | HOFFMANN-LA ROCHE INC. (US) | 1986-06-17 | — | — | US | disclosed |
| EP-0111695-A2 | Pyridazine derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-06-27 | — | — | EP | disclosed |
| EP-0002719-B1 | PROCESS FOR THE PREPARATION OF 3-PYRIDAZINONES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-06-24 | — | — | EP | disclosed |
| US-4255571-A | Catalytic dehydrogenation preparation of 3-pyridazones | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-03-10 | — | — | US | disclosed |
| EP-0002719-A2 | Process for the preparation of 3-pyridazinones | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-07-11 | — | — | EP | disclosed |