Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL23R | Q5VWK5 | 11/20 | 0.65 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.64 |
| ▸ | GLP1R | P43220 | 8/20 | 0.59 |
| ▸ | GCGR | P47871 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29461975 | 0.91 | C5AR1 (0.62) | IL23RC5AR1 | |
| SCHEMBL29461969 | 0.90 | C5AR1 (0.61) | IL23RC5AR1GLP1R | |
| SCHEMBL29700350 | 0.88 | IL23R (0.66) | IL23RGLP1R | |
| SCHEMBL31689355 | 0.88 | NPBWR1 (0.65) | IL23RC5AR1GLP1R | |
| SCHEMBL30518100 | 0.87 | C5AR1 (0.63) | IL23RC5AR1GLP1R | |
| SCHEMBL38654759 | 0.87 | C5AR1 (0.62) | IL23RC5AR1GLP1RGCGR | |
| SCHEMBL31680266 | 0.87 | GHSR (0.60) | IL23RC5AR1 | |
| SCHEMBL30451312 | 0.87 | C5AR1 (0.70) | IL23RC5AR1GLP1RGCGR | |
| SCHEMBL30592733 | 0.86 | GLP1R (0.55) | IL23RC5AR1GLP1RGCGR | |
| SCHEMBL31366714 | 0.86 | GLP1R (0.62) | IL23RC5AR1GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140378668-A1 | Tyrosine Bioconjugation through Aqueous Ene-Like Reactions | SCRIPPS RESEARCH INST (US) | 2014-12-25 | — | — | US | disclosed |
| US-8765920-B2 | Tyrosine bioconjugation through aqueous Ene-like reactions | THE SCRIPPS RESEARCH INSTITUTE (US) | 2014-07-01 | — | — | US | disclosed |
| US-20120289682-A1 | Tyrosine Bioconjugation through Aqueous Ene-Like Reactions | THE SCRIPPS RESEARCH INSTITUTE | 2012-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378668-A1 | Tyrosine Bioconjugation through Aqueous Ene-Like Reactions | TYR, DNPEP, TH | IL23R 1765/4885C5AR1 3674/4885GLP1R 404/4885 |
| US-20120289682-A1 | Tyrosine Bioconjugation through Aqueous Ene-Like Reactions | TYR, DNPEP, TH | IL23R 1765/4885C5AR1 3674/4885GLP1R 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.