Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.55 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.55 |
| ▸ | IL23R | Q5VWK5 | 7/20 | 0.54 |
| ▸ | GCGR | P47871 | 1/20 | 0.53 |
| ▸ | NPY2R | P49146 | 3/20 | 0.53 |
| ▸ | GHSR | Q92847 | 3/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.53 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.53 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31680258 | 0.93 | IL23R (0.58) | GLP1RIL23RGCGRNPY2RGHSR | |
| SCHEMBL31674340 | 0.93 | CCKBR (0.57) | GLP1RC5AR1IL23RGCGRTUBB4A | |
| SCHEMBL30132314 | 0.92 | TUBB4A (0.57) | GLP1RC5AR1IL23RNPY2RGHSR | |
| SCHEMBL29641170 | 0.92 | TUBB4A (0.57) | GLP1RC5AR1IL23RNPY2RGHSR | |
| SCHEMBL29641048 | 0.91 | IL23R (0.57) | GLP1RC5AR1IL23RGCGRTUBB4A | |
| SCHEMBL29641153 | 0.91 | C5AR1 (0.58) | GLP1RC5AR1IL23RGCGRNPY2R | |
| SCHEMBL29884974 | 0.91 | C5AR1 (0.58) | GLP1RC5AR1IL23RGCGRNPY2R | |
| SCHEMBL29461998 | 0.91 | C5AR1 (0.58) | GLP1RC5AR1IL23RGCGRNPY2R | |
| SCHEMBL29540499 | 0.91 | C5AR1 (0.58) | GLP1RC5AR1IL23RGCGRNPY2R | |
| SCHEMBL31680266 | 0.91 | GHSR (0.60) | C5AR1IL23RGHSRTUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260061023-A1 | METHODS AND COMPOSITIONS FOR THE PREVENTION OR TREATMENT OF BARTH SYNDROME | STEALTH BIOTHERAPEUTICS INC. (US) | 2026-03-05 | — | — | US | disclosed |
| US-12268724-B2 | Methods and compositions for the prevention or treatment of Barth Syndrome | STEALTH BIOTHERAPEUTICS INC. (US) | 2025-04-08 | — | — | US | disclosed |
| US-20240156892-A1 | METHODS AND COMPOSITIONS FOR THE PREVENTION OR TREATMENT OF BARTH SYNDROME | STEALTH BIOTHERAPEUTICS INC. (US) | 2024-05-16 | — | — | US | disclosed |
| US-11771734-B2 | Methods and compositions for the prevention or treatment of Barth syndrome | STEALTH BIOTHERAPEUTICS INC. (US) | 2023-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260061023-A1 | METHODS AND COMPOSITIONS FOR THE PREVENTION OR TREATMENT OF BARTH SYNDROME | ARG2, ARGLU1, BCAT1 | GLP1R 2295/4885C5AR1 4542/4885IL23R 3888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.