Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PLK1 | P53350 | 2/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6578806 | 0.83 | ALDH1A1 (0.64) | ALDH1A1LMNATUBB1HDAC1HDAC6 | |
| SCHEMBL8465292 | 0.80 | KDM4E (0.55) | ALDH1A1LMNATUBB1GAAKDM4E | |
| SCHEMBL7981473 | 0.79 | CES2 (0.56) | ALDH1A1HPGDPLK1HDAC1HDAC6 | |
| SCHEMBL4143482 | 0.78 | ALDH1A1 (0.77) | ALDH1A1HPGDLMNAPLK1MAPK1 | |
| SCHEMBL1003340 | 0.78 | ALDH1A1 (0.57) | ALDH1A1HPGDLMNAPLK1TUBB1 | |
| SCHEMBL507133 | 0.78 | LMNA (0.50) | ALDH1A1LMNATUBB1HTTMAPK1 | |
| SCHEMBL1458628 | 0.78 | LMNA (0.58) | ALDH1A1HPGDLMNATUBB1KDM4E | |
| SCHEMBL1004064 | 0.78 | HDAC6 (0.70) | ALDH1A1HPGDPLK1HDAC1HDAC6 | |
| SCHEMBL3129576 | 0.78 | MAPK1 (0.47) | ALDH1A1LMNATUBB1HDAC1HDAC6 | |
| SCHEMBL3138340 | 0.78 | MAPK1 (0.47) | ALDH1A1LMNATUBB1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8530467-B2 | Benzoimidazole compounds and uses thereof | NEOMED INSTITUTE (CA) | 2013-09-10 | — | — | US | disclosed |
| US-20120289504-A1 | Benzoimidazole Compounds and Uses Thereof | ASTRAZENECA AB (SE) | 2012-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120289504-A1 | Benzoimidazole Compounds and Uses Thereof | TPMT, BRD4, CYP3A4 | ALDH1A1 441/4885HPGD 1481/4885LMNA 2661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.