Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11975943 | 0.88 | ADRB3 (0.35) | ADRB3ADRA2BADRA2CALOX15HSD17B10 | |
| SCHEMBL8247428 | 0.87 | PSMB9 (0.34) | ADRB3ADRA2BADRA2CALOX15HSD17B10 | |
| SCHEMBL15706019 | 0.83 | CYP3A4 (0.39) | HDAC4HDAC1 | |
| SCHEMBL7923887 | 0.83 | PSMB9 (0.32) | ADRB3ADRA2BADRA2CMAPTKDM4E | |
| SCHEMBL8006962 | 0.82 | DPP4 (0.34) | ADRB3ADRA2BADRA2CMAPTKDM4E | |
| SCHEMBL18156074 | 0.80 | ALOX15 (0.31) | ALOX15HSD17B10 | |
| SCHEMBL13082484 | 0.79 | ADRB3 (0.37) | ADRB3ADRA2BADRA2CHDAC4HDAC1 | |
| SCHEMBL11983932 | 0.78 | ADRB3 (0.38) | ADRB3ADRA2BADRA2CALOX15HSD17B10 | |
| SCHEMBL13435865 | 0.78 | PSMB9 (0.32) | ALOX15HSD17B10MAPTKDM4EALDH1A1 | |
| SCHEMBL1645862 | 0.77 | ADRB3 (0.42) | ADRB3ADRA2BADRA2CALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151195-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-11-08 | — | — | WO | disclosed |