Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB9 | P28065 | 5/20 | 0.32 |
| ▸ | PPIA | P62937 | 3/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8247428 | 0.86 | PSMB9 (0.34) | PSMB9ADRB3ADRA2BADRA2CPSMB8 | |
| SCHEMBL13829859 | 0.83 | ADRB3 (0.33) | ADRB3ADRA2BADRA2CKDM4EALDH1A1 | |
| SCHEMBL8006962 | 0.79 | DPP4 (0.34) | ADRB3ADRA2BADRA2CKDM4EALDH1A1 | |
| SCHEMBL11975943 | 0.79 | ADRB3 (0.35) | ADRB3ADRA2BADRA2CKDM4EALDH1A1 | |
| SCHEMBL13435865 | 0.77 | PSMB9 (0.32) | PSMB9PSMB8KDM4EALDH1A1GAA | |
| SCHEMBL13896390 | 0.77 | ADRB3 (0.44) | ADRB3ADRA2BADRA2C | |
| SCHEMBL13082484 | 0.76 | ADRB3 (0.37) | ADRB3ADRA2BADRA2C | |
| SCHEMBL16938974 | 0.76 | FAP (0.34) | ADRB3ADRA2BADRA2C | |
| SCHEMBL11983932 | 0.76 | ADRB3 (0.38) | ADRB3ADRA2BADRA2C | |
| SCHEMBL7925281 | 0.74 | ADRB3 (0.33) | ADRB3ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033466-A1 | MACROCYCLIC INHIBITORS OF HEPATITIS C PROTEASE | PHENOMIX CORPORATION (US) | 2010-03-25 | — | — | WO | disclosed |