Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 11/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 11/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 11/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13830604 | 0.87 | PRSS1 (0.62) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL14898325 | 0.83 | PRSS1 (0.58) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL22652609 | 0.83 | PRSS1 (0.43) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL14898289 | 0.82 | PRSS1 (0.56) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL14898323 | 0.82 | PRSS1 (0.56) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL14898324 | 0.81 | PRSS1 (0.57) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL2110332 | 0.81 | PRSS1 (0.60) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL13830828 | 0.81 | PRSS1 (0.59) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL8047329 | 0.81 | PRSS1 (0.63) | PRSS1PRSS2PRSS3MAOAMAOB | |
| SCHEMBL15866799 | 0.80 | PRSS1 (0.55) | PRSS1PRSS2PRSS3MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200354319-A1 | MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | UNIV CORNELL (US) | 2020-11-12 | — | — | US | disclosed |
| US-20140194383-A1 | MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | CORNELL UNIVERSITY (US) | 2014-07-10 | — | — | US | disclosed |
| US-20140161729-A1 | COFLUORONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2014-06-12 | — | — | US | disclosed |
| US-20140161729-A1 | COFLUORONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2014-06-12 | — | — | US | disclosed |
| WO-2013058824-A1 | MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | CORNELL UNIVERSITY (US) | 2013-04-25 | — | — | WO | disclosed |
| WO-2012154213-A1 | COFLUORONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2012-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140161729-A1 | COFLUORONS AND METHODS OF MAKING AND USING THEM | TNFSF11, CD14, TNFRSF1A | PRSS1 4125/4885PRSS2 4301/4885PRSS3 4028/4885 |
| US-20200354319-A1 | MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | CALCOCO2, MDN1, MBNL1 | PRSS1 2733/4885PRSS2 2788/4885PRSS3 3354/4885 |
| US-20140194383-A1 | MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | CALCOCO2, MDN1, MBNL1 | PRSS1 2733/4885PRSS2 2788/4885PRSS3 3354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.