Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.45 |
| ▸ | MAPT | P10636 | 10/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | G6PC1 | P35575 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10037523 | 1.00 | MEN1 (0.45) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL12668490 | 0.93 | MEN1 (0.42) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL18087693 | 0.92 | MEN1 (0.41) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| Bromide SCHEMBL18074383 | 0.90 | MAPT (0.42) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| Bromide SCHEMBL18074379 | 0.90 | MAPT (0.42) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL2920143 | 0.89 | MEN1 (0.46) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL2920142 | 0.89 | MEN1 (0.46) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL2921302 | 0.89 | ACHE (0.47) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL2921507 | 0.89 | ACHE (0.47) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| Bromide SCHEMBL2923013 | 0.88 | MAPT (0.47) | MEN1KMT2AMAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8992633-B2 | Disulfide dyes | BASF SE (DE) | 2015-03-31 | — | — | US | disclosed |
| US-20140157529-A1 | DISULFIDE DYES | BASF SE (DE) | 2014-06-12 | — | — | US | disclosed |
| WO-2012150549-A1 | DISULFIDE DYES | BASF SE (DE) | 2012-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140157529-A1 | DISULFIDE DYES | KRT18, COL1A1, SULT1A1 | MEN1 4833/4885KMT2A 2729/4885MAPT 1432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.