Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13831843 | 0.94 | HTT (0.37) | LMNAMAPTNPC1RAB9AHPGD | |
| SCHEMBL13831775 | 0.91 | HPGD (0.43) | LMNAMAPTNPC1RAB9AHPGD | |
| SCHEMBL13831213 | 0.89 | LMNA (0.35) | LMNAMAPTNPC1RAB9AHPGD | |
| SCHEMBL13831475 | 0.89 | LMNA (0.35) | LMNAMAPTNPC1RAB9AHPGD | |
| SCHEMBL13831315 | 0.87 | SMN1; SMN2 (0.41) | LMNAMAPTNPC1RAB9AHPGD | |
| SCHEMBL13831409 | 0.86 | ALDH1A1 (0.39) | LMNAMAPTNPC1RAB9AHPGD | |
| SCHEMBL13832050 | 0.86 | MAPT (0.39) | LMNAMAPTNPC1RAB9AHPGD | |
| SCHEMBL13831011 | 0.80 | MAPT (0.41) | LMNAMAPTNPC1RAB9AHPGD | |
| SCHEMBL13831223 | 0.79 | MAPT (0.40) | LMNAMAPTNPC1RAB9AHPGD | |
| SCHEMBL13831537 | 0.79 | SMN1; SMN2 (0.52) | LMNAMAPTNPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230136150-A1 | Compositions for Inhibition of Insect Sensing | UNIV VANDERBILT (US) | 2023-05-04 | — | — | US | disclosed |
| US-20210219551-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2021-07-22 | — | — | US | disclosed |
| US-10813355-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2020-10-27 | — | — | US | disclosed |
| EP-2704575-B1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | UNIV VANDERBILT (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |
| US-20190075798-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2019-03-14 | — | — | US | disclosed |
| US-10188105-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2019-01-29 | — | — | US | disclosed |
| US-20170208809-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2017-07-27 | — | — | US | disclosed |
| US-9578881-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2017-02-28 | — | — | US | disclosed |
| US-20140242135-A1 | COMPOSITIONS FOR INHIBITION OF INSECT SENSING | VANDERBILT UNIVERSITY (US) | 2014-08-28 | — | — | US | disclosed |
| WO-2012154403-A9 | COMPOSITIONS FOR INHIBITION OF INSECT SENSING | VANDERBILT UNIVERSITY (US) | 2013-01-03 | — | — | WO | disclosed |
| WO-2012154403-A2 | COMPOSITION FOR INHIBITION OF INSECT SENSING | VANDERBILT UNIVERSITY (US) | 2012-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230136150-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | LMNA 4714/4885MAPT 1741/4885NPC1 538/4885 |
| US-10813355-B2 | Compositions for inhibition of insect sensing | OR51E2, TRPA1, OR10J3 | LMNA 4708/4885MAPT 2086/4885NPC1 577/4885 |
| US-20140242135-A1 | COMPOSITIONS FOR INHIBITION OF INSECT SENSING | OR51E2, TRPA1, OR10J3 | LMNA 4737/4885MAPT 1681/4885NPC1 527/4885 |
| US-20210219551-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | LMNA 4714/4885MAPT 1741/4885NPC1 538/4885 |
| US-10188105-B2 | Compositions for inhibition of insect sensing | OR51E2, TRPA1, OR10J3 | LMNA 4745/4885MAPT 2002/4885NPC1 573/4885 |
| US-20170208809-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | LMNA 4745/4885MAPT 2002/4885NPC1 573/4885 |
| US-20190075798-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | LMNA 4708/4885MAPT 2086/4885NPC1 577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.