Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20812798 | 0.89 | SMN1; SMN2 (0.50) | SMN1; SMN2TP53L3MBTL1ATMPOLB | |
| SCHEMBL13831826 | 0.89 | SMN1; SMN2 (0.49) | SMN1; SMN2TP53L3MBTL1ATMPOLB | |
| SCHEMBL15983249 | 0.88 | TP53 (0.57) | TP53L3MBTL1ATMPOLBSENP1 | |
| SCHEMBL13831366 | 0.87 | ALDH1A1 (0.58) | SMN1; SMN2LMNATSHRHTTNPSR1 | |
| SCHEMBL13832099 | 0.85 | TP53 (0.57) | SMN1; SMN2TP53L3MBTL1ATMPOLB | |
| SCHEMBL13831770 | 0.84 | TSHR (0.59) | SMN1; SMN2TP53L3MBTL1ATMTSHR | |
| SCHEMBL13832313 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2TP53L3MBTL1TDP1LMNA | |
| SCHEMBL13831105 | 0.83 | POLB (0.66) | SMN1; SMN2TP53L3MBTL1POLBTDP1 | |
| SCHEMBL13832100 | 0.83 | TP53 (0.74) | SMN1; SMN2TP53L3MBTL1ATMPOLB | |
| SCHEMBL15983400 | 0.82 | L3MBTL1 (0.67) | TP53L3MBTL1ATMPOLBSENP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230136150-A1 | Compositions for Inhibition of Insect Sensing | UNIV VANDERBILT (US) | 2023-05-04 | — | — | US | disclosed |
| US-20210219551-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2021-07-22 | — | — | US | disclosed |
| US-10813355-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2020-10-27 | — | — | US | disclosed |
| US-20190075798-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2019-03-14 | — | — | US | disclosed |
| US-10188105-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2019-01-29 | — | — | US | disclosed |
| US-20170208809-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2017-07-27 | — | — | US | disclosed |
| US-9578881-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2017-02-28 | — | — | US | disclosed |
| US-20140242135-A1 | COMPOSITIONS FOR INHIBITION OF INSECT SENSING | VANDERBILT UNIVERSITY (US) | 2014-08-28 | — | — | US | disclosed |
| WO-2012154403-A9 | COMPOSITIONS FOR INHIBITION OF INSECT SENSING | VANDERBILT UNIVERSITY (US) | 2013-01-03 | — | — | WO | disclosed |
| WO-2012154403-A2 | COMPOSITION FOR INHIBITION OF INSECT SENSING | VANDERBILT UNIVERSITY (US) | 2012-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230136150-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | SMN1; SMN2 4423/4885TP53 4604/4885L3MBTL1 1987/4885 |
| US-10813355-B2 | Compositions for inhibition of insect sensing | OR51E2, TRPA1, OR10J3 | SMN1; SMN2 4355/4885TP53 4651/4885L3MBTL1 1904/4885 |
| US-20140242135-A1 | COMPOSITIONS FOR INHIBITION OF INSECT SENSING | OR51E2, TRPA1, OR10J3 | SMN1; SMN2 4493/4885TP53 4606/4885L3MBTL1 2164/4885 |
| US-20210219551-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | SMN1; SMN2 4423/4885TP53 4604/4885L3MBTL1 1987/4885 |
| US-10188105-B2 | Compositions for inhibition of insect sensing | OR51E2, TRPA1, OR10J3 | SMN1; SMN2 4404/4885TP53 4649/4885L3MBTL1 2061/4885 |
| US-20170208809-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | SMN1; SMN2 4404/4885TP53 4649/4885L3MBTL1 2061/4885 |
| US-20190075798-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | SMN1; SMN2 4355/4885TP53 4651/4885L3MBTL1 1904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.