Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15983213 | 0.88 | LMNA (0.63) | LMNAALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL13832105 | 0.88 | LMNA (0.72) | LMNAALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL13831749 | 0.88 | TSHR (0.58) | LMNAALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL13831997 | 0.88 | ALDH1A1 (0.64) | LMNAALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL13831118 | 0.87 | LMNA (0.60) | LMNAALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL13831111 | 0.87 | LMNA (0.65) | LMNAALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL13831140 | 0.86 | LMNA (0.61) | LMNAALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL13831135 | 0.86 | ALDH1A1 (0.61) | LMNAALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL13831788 | 0.86 | ALDH1A1 (0.61) | LMNAALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL13831169 | 0.85 | LMNA (0.60) | LMNAALDH1A1TSHRKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230136150-A1 | Compositions for Inhibition of Insect Sensing | UNIV VANDERBILT (US) | 2023-05-04 | — | — | US | disclosed |
| US-20210219551-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2021-07-22 | — | — | US | disclosed |
| US-10813355-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2020-10-27 | — | — | US | disclosed |
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |
| US-20190075798-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2019-03-14 | — | — | US | disclosed |
| US-10188105-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2019-01-29 | — | — | US | disclosed |
| US-20170208809-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2017-07-27 | — | — | US | disclosed |
| US-9578881-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2017-02-28 | — | — | US | disclosed |
| US-20140242135-A1 | COMPOSITIONS FOR INHIBITION OF INSECT SENSING | VANDERBILT UNIVERSITY (US) | 2014-08-28 | — | — | US | disclosed |
| WO-2012154403-A9 | COMPOSITIONS FOR INHIBITION OF INSECT SENSING | VANDERBILT UNIVERSITY (US) | 2013-01-03 | — | — | WO | disclosed |
| WO-2012154403-A2 | COMPOSITION FOR INHIBITION OF INSECT SENSING | VANDERBILT UNIVERSITY (US) | 2012-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230136150-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | LMNA 4714/4885ALDH1A1 3579/4885TSHR 2971/4885 |
| US-10813355-B2 | Compositions for inhibition of insect sensing | OR51E2, TRPA1, OR10J3 | LMNA 4708/4885ALDH1A1 3568/4885TSHR 3088/4885 |
| US-20140242135-A1 | COMPOSITIONS FOR INHIBITION OF INSECT SENSING | OR51E2, TRPA1, OR10J3 | LMNA 4737/4885ALDH1A1 3549/4885TSHR 2891/4885 |
| US-20210219551-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | LMNA 4714/4885ALDH1A1 3579/4885TSHR 2971/4885 |
| US-10188105-B2 | Compositions for inhibition of insect sensing | OR51E2, TRPA1, OR10J3 | LMNA 4745/4885ALDH1A1 3533/4885TSHR 2976/4885 |
| US-20170208809-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | LMNA 4745/4885ALDH1A1 3533/4885TSHR 2976/4885 |
| US-20190075798-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | LMNA 4708/4885ALDH1A1 3568/4885TSHR 3088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.