Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14475971 | 0.81 | LMNA (0.60) | LMNASMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL13832127 | 0.77 | ALDH1A1 (0.60) | LMNASMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL13832265 | 0.76 | ALDH1A1 (0.60) | LMNASMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL13832114 | 0.75 | LMNA (0.58) | LMNASMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL13832116 | 0.75 | TP53 (0.56) | LMNASMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL13832136 | 0.74 | ALDH1A1 (0.69) | LMNASMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL13832332 | 0.74 | LMNA (0.58) | LMNASMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL22018792 | 0.74 | LMNA (0.49) | LMNASMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL13832084 | 0.74 | ALDH1A1 (0.53) | LMNAKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL13831453 | 0.72 | ALDH1A1 (0.50) | LMNAKDM4EALDH1A1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012154403-A2 | COMPOSITION FOR INHIBITION OF INSECT SENSING | VANDERBILT UNIVERSITY (US) | 2012-11-15 | — | — | WO | disclosed |