Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13832265 | 0.86 | ALDH1A1 (0.60) | LMNAALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL14475971 | 0.83 | LMNA (0.60) | LMNAALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL13832127 | 0.82 | ALDH1A1 (0.60) | LMNAALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL13832084 | 0.82 | ALDH1A1 (0.53) | LMNAALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL13832114 | 0.82 | LMNA (0.58) | LMNAALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL13832136 | 0.81 | ALDH1A1 (0.69) | LMNAALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL13832332 | 0.81 | LMNA (0.58) | LMNAALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL13832116 | 0.80 | TP53 (0.56) | LMNAALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL13832137 | 0.74 | LMNA (0.41) | LMNAALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL13831304 | 0.73 | NPSR1 (0.54) | LMNAALDH1A1MAPTPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |