SCHEMBL13832168

SCHEMBL13832168

Cc1cccc(N(c2cccc(C)c2)c2ccc3c4c(cccc24)-c2ccccc2-3)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.41
KDM4E B2RXH2 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
PABPC1 P11940 2/20 0.41
MEN1 O00255 7/20 0.40
KMT2A Q03164 7/20 0.40
ALDH1A1 P00352 4/20 0.40
USP2 O75604 4/20 0.40
KEAP1 Q14145 3/20 0.40
NFE2L2 Q16236 3/20 0.40
CASP1 P29466 3/20 0.40
HSD17B10 Q99714 3/20 0.40
HPGD P15428 2/20 0.40
HTT P42858 2/20 0.40
CASP7 P55210 2/20 0.40
HBB P68871 2/20 0.40
TP53 P04637 1/20 0.40
CRHBP P24387 2/20 0.40
CRHR2 Q13324 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14010643 0.93 MEN1 (0.37) MAPTKDM4ESMN1; SMN2PABPC1MEN1
SCHEMBL2329975 0.93 MEN1 (0.38) MAPTKDM4ESMN1; SMN2PABPC1MEN1
SCHEMBL14069727 0.89 MEN1 (0.36) MAPTKDM4ESMN1; SMN2PABPC1MEN1
SCHEMBL14010656 0.89 MEN1 (0.36) MAPTKDM4ESMN1; SMN2PABPC1MEN1
SCHEMBL13831565 0.87 NQO2 (0.41) MAPTKDM4ESMN1; SMN2PABPC1MEN1
SCHEMBL13367475 0.86 MEN1 (0.43) MAPTKDM4ESMN1; SMN2PABPC1MEN1
SCHEMBL10128581 0.85 ACHE (0.42) MAPTKDM4EALDH1A1USP2HSD17B10
SCHEMBL10128557 0.84 KDM4E (0.41) MAPTKDM4ESMN1; SMN2PABPC1MEN1
SCHEMBL13358328 0.84 APP (0.37) MAPTKDM4ESMN1; SMN2PABPC1MEN1
SCHEMBL10072075 0.84 KDM4E (0.42) MAPTKDM4ESMN1; SMN2PABPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012153083-A1 LIGHT EMITTING MATERIAL, COMPOSITION AND DEVICE CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2012-11-15 WO disclosed
US-7186490-B1 Photosensitive material, electrophotographic photoreceptor using the material, and electrophotographic image forming method and apparatus using the photoreceptor RICOH COMPANY, LTD. (JP) 2007-03-06 US disclosed
US-7186490-B1 Photosensitive material, electrophotographic photoreceptor using the material, and electrophotographic image forming method and apparatus using the photoreceptor RICOH COMPANY, LTD. (JP) 2007-03-06 US disclosed