SCHEMBL14010643

SCHEMBL14010643

Cc1cccc(N(c2ccc(-c3ccc(N(c4cccc(C)c4)c4ccc5c6c(cccc46)-c4ccccc4-5)cc3)cc2)c2ccc3c4c(cccc24)-c2ccccc2-3)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.37
KMT2A Q03164 7/20 0.37
MAPT P10636 6/20 0.37
ALDH1A1 P00352 4/20 0.37
USP2 O75604 4/20 0.37
KDM4E B2RXH2 3/20 0.37
KEAP1 Q14145 3/20 0.37
NFE2L2 Q16236 3/20 0.37
CASP1 P29466 3/20 0.37
HSD17B10 Q99714 3/20 0.37
HPGD P15428 2/20 0.37
HTT P42858 2/20 0.37
CASP7 P55210 2/20 0.37
HBB P68871 2/20 0.37
TP53 P04637 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
PABPC1 P11940 1/20 0.36
CRHBP P24387 2/20 0.35
CRHR2 Q13324 2/20 0.35
HSD17B1 P14061 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13832168 0.93 MAPT (0.41) MEN1KMT2AMAPTALDH1A1USP2
SCHEMBL13358328 0.91 APP (0.37) MEN1KMT2AMAPTALDH1A1USP2
SCHEMBL2329975 0.89 MEN1 (0.38) MEN1KMT2AMAPTALDH1A1USP2
SCHEMBL14010644 0.89 KDM4E (0.40) MEN1KMT2AMAPTALDH1A1USP2
SCHEMBL14069727 0.88 MEN1 (0.36) MEN1KMT2AMAPTALDH1A1USP2
SCHEMBL5002787 0.87 CRHBP (0.42) MEN1KMT2AMAPTALDH1A1USP2
SCHEMBL14069728 0.86 CRHR1 (0.35) MEN1KMT2AMAPTALDH1A1USP2
SCHEMBL23764165 0.86 MAPT (0.38) MEN1KMT2AMAPTALDH1A1USP2
SCHEMBL14491557 0.86 MEN1 (0.38) MEN1KMT2AMAPTALDH1A1USP2
SCHEMBL23546674 0.86 CRHBP (0.41) MEN1KMT2AMAPTALDH1A1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080278065-A1 Organic Electroluminescent Element and Display Apparatus SONY CORPORATION (JP) 2008-11-13 US disclosed
US-20080278065-A1 Organic Electroluminescent Element and Display Apparatus SONY CORPORATION (JP) 2008-11-13 US disclosed
US-20070149815-A1 Organic light-emitting material and method for producing an organic material SONY CORPORATION (JP) 2007-06-28 US disclosed
US-20070149815-A1 Organic light-emitting material and method for producing an organic material SONY CORPORATION (JP) 2007-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070149815-A1 Organic light-emitting material and method for producing an organic material CRY1, CRY2, IK MEN1 524/4885KMT2A 1068/4885MAPT 1013/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.