Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038764 | 0.89 | SMN1; SMN2 (0.49) | ALDH1A1MEN1KMT2ANOTUMTSHR | |
| SCHEMBL8979214 | 0.75 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL5698473 | 0.75 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL27564281 | 0.74 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL5120536 | 0.73 | NOTUM (0.50) | ALDH1A1MEN1KMT2ANOTUMTSHR | |
| SCHEMBL7126729 | 0.73 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ANOTUMTSHR | |
| SCHEMBL29985725 | 0.73 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ANOTUMTSHR | |
| SCHEMBL307373 | 0.73 | TSHR (0.45) | ALDH1A1MEN1KMT2ANOTUMTSHR | |
| SCHEMBL28654768 | 0.73 | SMN1; SMN2 (0.46) | ALDH1A1MEN1KMT2ANOTUMTSHR | |
| SCHEMBL2203263 | 0.72 | NPC1 (0.50) | ALDH1A1MEN1KMT2AUSP2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105518005-B | Tricyclic pyridine-carboxamide derivatives as ROCK inhibitors | 百时美施贵宝公司 | 2018-07-20 | — | — | CN | claimed |
| CN-105073741-B | Phthalazinones and isoquinolinones as ROCK inhibitors | 百时美施贵宝公司 | 2017-08-08 | — | — | CN | claimed |
| CN-104540806-B | Azaheterocycles as BIR2 and/or BIR3 inhibitors | 霍夫曼-拉罗奇有限公司 | 2017-05-03 | — | — | CN | claimed |
| CN-102725292-A | Imidazopyridine compounds as novel constructs for multi-target kinase inhibition | ABBOTT LAB | 2012-10-10 | — | — | CN | claimed |
| JP-4838934-B2 | — | — | 2011-12-14 | — | — | JP | claimed |
| EP-1042291-A1 | ARYL-SUBSTITUTED PYRIDYLALKANE, ALKENE, AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS | Klinge Pharma GmbH (DE) | 2000-10-11 | — | — | EP | claimed |
| WO-1999031064-A1 | ARYL-SUBSTITUTED PYRIDYLALKANE, ALKENE, AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS | KLINGE PHARMA GMBH (DE) | 1999-06-24 | — | — | WO | claimed |
| US-12391666-B2 | Indoline-1-formamide compound, preparation method therefor, and medical use thereof | BEIJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2025-08-19 | — | — | US | disclosed |
| CN-112384506-B | Indoline-1-formamide compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-112384506-B | Indoline-1-formamide compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-112384506-B | Indoline-1-formamide compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-112384506-A | Indoline-1-formamide compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-112384506-A | Indoline-1-formamide compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-105073741-B | Phthalazinones and isoquinolinones as ROCK inhibitors | 百时美施贵宝公司 | 2017-08-08 | — | — | CN | disclosed |
| CN-106817899-A | Spiroheptane as ROCK inhibitor | 百时美施贵宝公司 | 2017-06-09 | — | — | CN | disclosed |
| CN-102725292-A | Imidazopyridine compounds as novel constructs for multi-target kinase inhibition | ABBOTT LAB | 2012-10-10 | — | — | CN | disclosed |
| US-7320993-B1 | Aryl-substituted pyridylalkane, alkene, and alkine carboxamides useful as cytostatic useful as cytostatic and immuosuppressive agents | ASTELLAS DEUTSCHLAND GMBH (DE) | 2008-01-22 | — | — | US | disclosed |
| CN-1658759-A | Insecticidal amides with nitrogen-containing benzo-fused bicyclic ring systems | DU PONT (US) | 2005-08-24 | — | — | CN | disclosed |
| US-4619784-A | XANTHENE DERIVATIVES | POLAROID CORPORATION, PATENT DEPT. (US) | 1986-10-28 | — | — | US | disclosed |
| US-4267251-A | DIFFUSION TRANSFER | POLAROID CORPORATION (US) | 1981-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12391666-B2 | Indoline-1-formamide compound, preparation method therefor, and medical use thereof | FLT1, KDR, TEK | ALDH1A1 783/4885MEN1 342/4885KMT2A 1659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.