Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.47 |
| ▸ | S100A10 | P60903 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13832328 | 0.90 | POLB (0.61) | POLBLMNAUSP2HSD17B10KMT2A | |
| SCHEMBL13831465 | 0.85 | GAA (0.50) | POLBLMNAUSP2KMT2AMAPT | |
| SCHEMBL13832330 | 0.84 | LMNA (0.45) | POLBLMNAUSP2KMT2AMAPT | |
| SCHEMBL15986441 | 0.83 | POLB (0.83) | POLBLMNAUSP2HSD17B10KMT2A | |
| SCHEMBL15983288 | 0.83 | ALDH1A1 (0.56) | POLBLMNAUSP2HSD17B10KMT2A | |
| SCHEMBL13832032 | 0.82 | ALDH1A1 (0.51) | POLBLMNAHSD17B10KMT2ASMN1; SMN2 | |
| SCHEMBL13831065 | 0.82 | NPSR1 (0.58) | POLBLMNAUSP2KMT2AMAPT | |
| SCHEMBL13831599 | 0.81 | ALDH1A1 (0.60) | POLBLMNAUSP2KMT2ASMN1; SMN2 | |
| SCHEMBL13832319 | 0.81 | POLB (0.59) | POLBLMNAUSP2HSD17B10KMT2A | |
| SCHEMBL13832337 | 0.81 | POLB (0.59) | POLBLMNAUSP2HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230136150-A1 | Compositions for Inhibition of Insect Sensing | UNIV VANDERBILT (US) | 2023-05-04 | — | — | US | disclosed |
| US-20230136150-A1 | Compositions for Inhibition of Insect Sensing | UNIV VANDERBILT (US) | 2023-05-04 | — | — | US | disclosed |
| US-20210219551-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2021-07-22 | — | — | US | disclosed |
| US-10813355-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2020-10-27 | — | — | US | disclosed |
| EP-2704575-B1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | UNIV VANDERBILT (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |
| US-20190075798-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2019-03-14 | — | — | US | disclosed |
| US-10188105-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2019-01-29 | — | — | US | disclosed |
| US-20170208809-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2017-07-27 | — | — | US | disclosed |
| US-20170208809-A1 | Compositions for Inhibition of Insect Sensing | VANDERBILT UNIVERSITY | 2017-07-27 | — | — | US | disclosed |
| US-9578881-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2017-02-28 | — | — | US | disclosed |
| US-9578881-B2 | Compositions for inhibition of insect sensing | VANDERBILT UNIVERSITY (US) | 2017-02-28 | — | — | US | disclosed |
| US-20140242135-A1 | COMPOSITIONS FOR INHIBITION OF INSECT SENSING | VANDERBILT UNIVERSITY (US) | 2014-08-28 | — | — | US | disclosed |
| US-20140242135-A1 | COMPOSITIONS FOR INHIBITION OF INSECT SENSING | VANDERBILT UNIVERSITY (US) | 2014-08-28 | — | — | US | disclosed |
| WO-2012154403-A9 | COMPOSITIONS FOR INHIBITION OF INSECT SENSING | VANDERBILT UNIVERSITY (US) | 2013-01-03 | — | — | WO | disclosed |
| WO-2012154403-A2 | COMPOSITION FOR INHIBITION OF INSECT SENSING | VANDERBILT UNIVERSITY (US) | 2012-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230136150-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | POLB 4840/4885LMNA 4714/4885USP2 2348/4885 |
| US-10813355-B2 | Compositions for inhibition of insect sensing | OR51E2, TRPA1, OR10J3 | POLB 4832/4885LMNA 4708/4885USP2 2256/4885 |
| US-20140242135-A1 | COMPOSITIONS FOR INHIBITION OF INSECT SENSING | OR51E2, TRPA1, OR10J3 | POLB 4842/4885LMNA 4737/4885USP2 2433/4885 |
| US-20210219551-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | POLB 4840/4885LMNA 4714/4885USP2 2348/4885 |
| US-10188105-B2 | Compositions for inhibition of insect sensing | OR51E2, TRPA1, OR10J3 | POLB 4834/4885LMNA 4745/4885USP2 2329/4885 |
| US-20170208809-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | POLB 4834/4885LMNA 4745/4885USP2 2329/4885 |
| US-20190075798-A1 | Compositions for Inhibition of Insect Sensing | OR51E2, TRPA1, OR10J3 | POLB 4832/4885LMNA 4708/4885USP2 2256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.