Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.47 |
| ▸ | MTOR | P42345 | 5/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1994355 | 0.73 | GAA (1.00) | GAAKDM4EHTTPIK3CAMTOR | |
| SCHEMBL2776064 | 0.72 | GAA (0.53) | GAAKMT2AMEN1POLBKDM4E | |
| SCHEMBL8973821 | 0.72 | HTT (0.63) | GAAKMT2AMEN1POLBKDM4E | |
| SCHEMBL1443593 | 0.71 | PIK3CA (0.61) | GAAKDM4EHTTPIK3CAMTOR | |
| SCHEMBL1396153 | 0.71 | PKM (0.58) | GAAKMT2AKDM4EHTTPIK3CA | |
| SCHEMBL11680654 | 0.71 | MEN1 (0.53) | GAAKMT2AMEN1POLBKDM4E | |
| SCHEMBL9418611 | 0.70 | HTT (0.61) | GAAKMT2AMEN1POLBKDM4E | |
| SCHEMBL8607492 | 0.70 | KDM4E (0.57) | GAAKMT2AKDM4EHTTPIK3CA | |
| Hydrochloric Acid SCHEMBL30702225 | 0.70 | PIK3CA (0.59) | GAAKDM4EHTTPIK3CAMTOR | |
| SCHEMBL1458406 | 0.68 | PIK3CA (0.54) | GAAKMT2AKDM4EHTTPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2707487-B1 | RIBOSWITCHES | UNIV MANCHESTER (GB) | 2017-10-04 | — | — | EP | disclosed |
| US-20140213779-A1 | RIBOSWITCHES | THE UNIVERSITY OF MANCHESTER (GB) | 2014-07-31 | — | — | US | disclosed |
| US-20140213779-A1 | RIBOSWITCHES | THE UNIVERSITY OF MANCHESTER (GB) | 2014-07-31 | — | — | US | disclosed |
| WO-2012153142-A2 | RIBOSWITCHES | THE UNIVERSITY OF MANCHESTER (GB) | 2012-11-15 | — | — | WO | disclosed |