Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 6/20 | 0.41 |
| ▸ | MTOR | P42345 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17822225 | 0.79 | GAA (0.39) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL30677407 | 0.76 | GAA (0.47) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL8607492 | 0.74 | KDM4E (0.57) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL3957743 | 0.73 | CYP1A2 (0.39) | GAAALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL13833291 | 0.72 | GAA (0.57) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL19414284 | 0.70 | HTR2A (0.58) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL1994355 | 0.69 | GAA (1.00) | GAAKDM4EALDH1A1PIK3CAPIK3R1 | |
| SCHEMBL8264499 | 0.69 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL8973821 | 0.69 | HTT (0.63) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1443593 | 0.68 | PIK3CA (0.61) | GAAKDM4EALDH1A1GLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790877-B2 | Antisense oligonucleotides with increased RNase sensitivity | GEN-PROBE, INCORPORATED (US) | 2010-09-07 | — | — | US | disclosed |
| EP-1019539-A4 | COMBINATORIAL ANTISENSE LIBRARY | GEN PROBE INC (US) | 2005-03-09 | — | — | EP | disclosed |
| EP-1019539-A1 | COMBINATORIAL ANTISENSE LIBRARY | Oasis Biosciences, Inc. (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999018238-A1 | COMBINATORIAL ANTISENSE LIBRARY | OASIS BIOSCIENCES, INC. (US) | 1999-04-15 | — | — | WO | disclosed |