Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13833594 | 0.84 | DHFR (0.47) | DHFREGFRKDR | |
| SCHEMBL2915133 | 0.82 | DHFR (0.46) | DHFREGFRKDR | |
| SCHEMBL5861834 | 0.74 | DHFR (0.46) | DHFREGFRKDR | |
| SCHEMBL5861670 | 0.72 | — | — | |
| SCHEMBL6310645 | 0.72 | DHFR (0.47) | DHFREGFRKDR | |
| SCHEMBL6311077 | 0.72 | MBOAT4 (0.78) | DHFR | |
| SCHEMBL4871146 | 0.71 | DHFR (0.47) | DHFREGFRKDR | |
| SCHEMBL19417781 | 0.71 | DHFR (0.40) | DHFREGFRKDR | |
| SCHEMBL13833428 | 0.70 | DHFR (0.41) | DHFRKDR | |
| SCHEMBL6304456 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2707487-B1 | RIBOSWITCHES | UNIV MANCHESTER (GB) | 2017-10-04 | — | — | EP | disclosed |
| US-20140213779-A1 | RIBOSWITCHES | THE UNIVERSITY OF MANCHESTER (GB) | 2014-07-31 | — | — | US | disclosed |
| US-20140213779-A1 | RIBOSWITCHES | THE UNIVERSITY OF MANCHESTER (GB) | 2014-07-31 | — | — | US | disclosed |
| WO-2012153142-A2 | RIBOSWITCHES | THE UNIVERSITY OF MANCHESTER (GB) | 2012-11-15 | — | — | WO | disclosed |