Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 14/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15519718 | 0.73 | EGFR (0.38) | PDE7APOLBPDE4BALDH1A1SMN1; SMN2 | |
| SCHEMBL15801427 | 0.73 | PDE4B (0.46) | PDE7APDE4BSMN1; SMN2 | |
| SCHEMBL1703867 | 0.69 | POLB (0.74) | PDE7APOLBPDE4BMAPTALDH1A1 | |
| SCHEMBL7891889 | 0.69 | L3MBTL1 (0.62) | PDE7APOLBPDE4BL3MBTL1PDE7B | |
| SCHEMBL25360850 | 0.67 | POLB (0.52) | PDE7APOLBPDE4BL3MBTL1PDE7B | |
| SCHEMBL7010705 | 0.67 | PDE7A (0.52) | PDE7APOLBPDE4BL3MBTL1PDE7B | |
| SCHEMBL7966891 | 0.67 | PDE7A (0.50) | PDE7APDE4BL3MBTL1PDE7BLMNA | |
| SCHEMBL6222959 | 0.67 | ALDH1A1 (0.63) | PDE7APOLBPDE4BL3MBTL1LMNA | |
| SCHEMBL13467800 | 0.67 | L3MBTL1 (0.80) | PDE7APDE4BL3MBTL1PDE7BLMNA | |
| SCHEMBL13833572 | 0.66 | CASR (0.48) | PDE7APDE4BPDE7BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012153796-A1 | PYRIMIDO-DIAZEPINONE COMPOUND | 協和発酵キリン株式会社 (JP) | 2012-11-15 | — | — | WO | disclosed |