Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.59 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | EDNRB | P24530 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | MC3R | P41968 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27814502 | 0.94 | GABBR2 (0.69) | ALDH1A1CYP2D6CYP1A2PKMSMN1; SMN2 | |
| SCHEMBL16588649 | 0.90 | ALDH1A1 (0.59) | ALDH1A1CYP2D6CYP1A2PKMSMN1; SMN2 | |
| SCHEMBL21758203 | 0.90 | ALDH1A1 (0.55) | ALDH1A1CYP2D6CYP1A2PKMSMN1; SMN2 | |
| SCHEMBL27691658 | 0.90 | GABBR2 (0.75) | ALDH1A1CYP2D6CYP1A2PKMSMN1; SMN2 | |
| SCHEMBL8192677 | 0.90 | CYP2D6 (0.56) | ALDH1A1CYP2D6CYP1A2PKMSMN1; SMN2 | |
| SCHEMBL1059563 | 0.90 | CYP2D6 (0.56) | ALDH1A1CYP2D6CYP1A2PKMSMN1; SMN2 | |
| SCHEMBL8187229 | 0.90 | CYP2D6 (0.56) | ALDH1A1CYP2D6CYP1A2PKMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3666598 | 0.89 | ALDH1A1 (0.54) | ALDH1A1CYP2D6CYP1A2PKMSMN1; SMN2 | |
| SCHEMBL186231 | 0.88 | ALDH1A1 (0.56) | ALDH1A1CYP2D6CYP1A2PKMSMN1; SMN2 | |
| SCHEMBL186239 | 0.88 | ALDH1A1 (0.56) | ALDH1A1CYP2D6CYP1A2PKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102753702-B | Process for preparing optically active 3-substituted glutaric acid monoamides | KANEKA CORP | 2015-02-11 | — | — | CN | disclosed |
| CN-102753702-A | Process for preparing optically active 3-substituted glutaric acid monoamides | KANEKA CORP | 2012-10-24 | — | — | CN | disclosed |
| EP-2460885-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 3-SUBSTITUTED GLUTARIC ACID MONOAMIDE | Kaneka Corporation (JP) | 2012-06-06 | — | — | EP | disclosed |
| EP-0024776-B1 | 4-PHENYL AND 5-PHENYL-1,4,5,6-TETRAHYDROPYRIMIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES, AND PROCESS FOR PREPARING SAID DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1984-12-27 | — | — | EP | disclosed |
| US-4322421-A | 4-Phenyl-and 5-phenyl-1,4,5,6-tetrahydro-pyrimidine derivatives | SYNTEX (U.S.A.) INC. (US) | 1982-03-30 | — | — | US | disclosed |
| US-4261995-A | DISORDERS OF CENTRAL NERVOUS SYSTEM AND CARDIOVASCULAR SYSTEM; HYPOTENSIVE | SYNTEX (U.S.A.) INC. (US) | 1981-04-14 | — | — | US | disclosed |
| EP-0024776-A1 | 4-Phenyl and 5-phenyl-1,4,5,6-tetrahydropyrimidine derivatives, pharmaceutical compositions containing said derivatives, and process for preparing said derivatives | SYNTEX (U.S.A.) INC. (US) | 1981-03-11 | — | — | EP | disclosed |