Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAPDH | P04406 | 2/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | HSPA8 | P11142 | 3/20 | 0.67 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.66 |
| ▸ | SLC28A2 | O43868 | 4/20 | 0.65 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | NADK | O95544 | 1/20 | 0.60 |
| ▸ | PDE4A | P27815 | 1/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.59 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.59 |
| ▸ | ADK | P55263 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13835106 | 1.00 | GAPDH (0.70) | GAPDHHSD17B10HSPA8HSPA5ADORA3 | |
| SCHEMBL30316415 | 0.90 | CYP3A4 (0.67) | GAPDHHSD17B10HSPA8HSPA5ADORA3 | |
| SCHEMBL7258957 | 0.90 | HSPA8 (0.66) | GAPDHHSD17B10HSPA8HSPA5ADORA3 | |
| SCHEMBL578218 | 0.90 | CYP3A4 (0.67) | GAPDHHSD17B10HSPA8HSPA5ADORA3 | |
| SCHEMBL3485985 | 0.90 | CYP3A4 (0.67) | GAPDHHSD17B10HSPA8HSPA5ADORA3 | |
| SCHEMBL7258948 | 0.90 | HSPA8 (0.66) | GAPDHHSD17B10HSPA8HSPA5ADORA3 | |
| SCHEMBL30237448 | 0.89 | HSD17B10 (0.56) | GAPDHHSD17B10HSPA8HSPA5ADORA3 | |
| SCHEMBL13834974 | 0.88 | SLC28A2 (0.68) | GAPDHHSD17B10HSPA8HSPA5SLC28A2 | |
| SCHEMBL13834979 | 0.88 | SLC28A2 (0.68) | GAPDHHSD17B10HSPA8HSPA5SLC28A2 | |
| SCHEMBL7258733 | 0.87 | HSPA8 (0.68) | GAPDHHSD17B10HSPA8HSPA5ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2707483-B1 | METHODS AND MATERIALS FOR NUCLEIC ACID MANIPULATION | RWTH AACHEN UNIV (DE) | 2017-10-18 | — | — | EP | disclosed |
| US-20120295311-A1 | Methods and Materials for Nucleic Acid Manipulation | BASF SE (DE) | 2012-11-22 | — | — | US | disclosed |