SCHEMBL7258733

SCHEMBL7258733

Nc1ncnc2c1nc(Sc1ncccn1)n2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.74

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSPA8 P11142 4/20 0.68
HSPA5 P11021 3/20 0.68
GAPDH P04406 2/20 0.63
HSD17B10 Q99714 1/20 0.63
RXFP1 Q9HBX9 1/20 0.62
LMNA P02545 1/20 0.59
TP53 P04637 1/20 0.59
HBB P68871 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
ADORA3 P0DMS8 3/20 0.59
SLC28A2 O43868 3/20 0.58
ADORA2A P29274 1/20 0.58
NADK O95544 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13835106 0.87 GAPDH (0.70) HSPA8HSPA5GAPDHHSD17B10RXFP1
SCHEMBL13835110 0.87 GAPDH (0.70) HSPA8HSPA5GAPDHHSD17B10RXFP1
SCHEMBL6761772 0.85 HSPA8 (0.73) HSPA8HSPA5GAPDHHSD17B10RXFP1
SCHEMBL6761778 0.85 HSPA8 (0.73) HSPA8HSPA5GAPDHHSD17B10RXFP1
SCHEMBL4754902 0.84 SLC28A2 (0.64) HSPA8HSPA5GAPDHHSD17B10RXFP1
SCHEMBL7258957 0.83 HSPA8 (0.66) HSPA8HSPA5GAPDHHSD17B10RXFP1
SCHEMBL30316415 0.83 CYP3A4 (0.67) HSPA8HSPA5GAPDHHSD17B10RXFP1
SCHEMBL7258948 0.83 HSPA8 (0.66) HSPA8HSPA5GAPDHHSD17B10RXFP1
SCHEMBL3485985 0.83 CYP3A4 (0.67) HSPA8HSPA5GAPDHHSD17B10RXFP1
SCHEMBL578218 0.83 CYP3A4 (0.67) HSPA8HSPA5GAPDHHSD17B10RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003051881-A1 SUBSTITUTED PURINE NUCLEOSIDE LIBRARIES AND COMPOUNDS BY SOLID-PHASE COMBINATORIAL STRATEGIES RIBAPHARM INC. (US) 2003-06-26 WO disclosed