Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13835830 | 1.00 | LIPE (1.00) | LIPE | |
| SCHEMBL13836111 | 1.00 | LIPE (1.00) | LIPE | |
| SCHEMBL16564305 | 0.88 | LIPE (0.79) | LIPE | |
| SCHEMBL13836110 | 0.88 | LIPE (1.00) | LIPE | |
| SCHEMBL13835979 | 0.88 | LIPE (1.00) | LIPE | |
| SCHEMBL16564306 | 0.84 | LIPE (0.70) | LIPE | |
| SCHEMBL13836263 | 0.82 | LIPE (1.00) | LIPE | |
| SCHEMBL13836129 | 0.82 | LIPE (1.00) | LIPE | |
| SCHEMBL13835855 | 0.81 | LIPE (1.00) | LIPE | |
| SCHEMBL13836280 | 0.81 | LIPE (1.00) | LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120295934-A1 | New Hexahydrocyclopentapyrrolone, Hexahydropyrrolopyrrolone, Octahydropyrrolopyridinone and Octahydropyridinone Compounds | F. HOFFMANN-LA ROCHE AG (CH) | 2012-11-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295934-A1 | New Hexahydrocyclopentapyrrolone, Hexahydropyrrolopyrrolone, Octahydropyrrolopyridinone and Octahydropyridinone Compounds | LIPE, LIPC, PNLIP | LIPE 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.