Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.55 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383560 | 1.00 | MAPT (0.55) | MAPTABCB1CACNA1GKMT2AMAPK1 | |
| SCHEMBL7493514 | 0.89 | MAPT (0.54) | MAPTKMT2AMAPK1ALDH1A1LMNA | |
| SCHEMBL7492035 | 0.89 | MAPT (0.54) | MAPTKMT2AMAPK1ALDH1A1LMNA | |
| SCHEMBL7492021 | 0.89 | MAPT (0.54) | MAPTKMT2AMAPK1ALDH1A1LMNA | |
| SCHEMBL7564923 | 0.87 | HTR1A (0.52) | MAPTABCB1CACNA1GMAPK1ALDH1A1 | |
| SCHEMBL7564915 | 0.87 | HTR1A (0.52) | MAPTABCB1CACNA1GMAPK1ALDH1A1 | |
| SCHEMBL7489075 | 0.86 | ABCB1 (0.48) | ABCB1L3MBTL1ALDH1A1 | |
| SCHEMBL1380843 | 0.86 | ABCB1 (0.48) | ABCB1L3MBTL1ALDH1A1 | |
| SCHEMBL7497905 | 0.86 | HTR2A (0.51) | — | |
| SCHEMBL7500542 | 0.86 | HTR2A (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4806149-B2 | — | — | 2011-11-02 | — | — | JP | claimed |
| EP-1216244-A1 | Benzisoxazolyl-, pyridoisoxazolyl- and benzthienyl-phenoxy derivatives useful as D4 antagonists | Aventis Pharmaceuticals Inc. (US) | 2002-06-26 | — | — | EP | claimed |
| WO-2001019821-A1 | BENZISOXAZOLYL-, PYRIDOISOXAZOLYL- AND BENZTHIENYL-PHENOXY DERIVATIVES USEFUL AS D4 ANTAGONISTS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-03-22 | — | — | WO | claimed |