Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.32 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13976379 | 0.82 | BCHE (0.44) | ADORA1ADORA2AADORA2BADORA3KMT2A | |
| SCHEMBL8009119 | 0.81 | CDK1 (0.52) | CDK1KMT2ACDK2 | |
| SCHEMBL15185178 | 0.80 | CDK1 (0.39) | CDK1ADORA1ADORA2AADORA2BADORA3 | |
| SCHEMBL16146951 | 0.79 | ADORA2A (0.41) | CDK1ADORA1ADORA2AADORA2BADORA3 | |
| Trifluoroacetic Acid SCHEMBL3132981 | 0.77 | HRH4 (0.38) | CDK1ADORA1ADORA2AADORA2BADORA3 | |
| SCHEMBL10047091 | 0.76 | CDK1 (0.33) | CDK1ADORA1ADORA2AADORA2BADORA3 | |
| SCHEMBL1146235 | 0.76 | ADORA2A (0.44) | CDK1ADORA1ADORA2AADORA2BADORA3 | |
| SCHEMBL9792866 | 0.76 | APP (0.57) | ADORA1ADORA2AADORA2BADORA3KMT2A | |
| SCHEMBL611824 | 0.75 | STK17B (0.47) | ADORA1ADORA2AADORA2BKDM4EKMT2A | |
| SCHEMBL10047120 | 0.75 | L3MBTL1 (0.38) | CDK1ADORA1ADORA2AADORA3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150323542-A1 | FLUORESCENT MOLECULAR PROBES FOR USE IN ASSAYS THAT MEASURE TEST COMPOUND COMPETITIVE BINDING WITH SAM-UTILIZING PROTEINS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2015-11-12 | — | — | US | disclosed |
| US-20150322107-A1 | FLUORESCENT MOLECULAR PROBES FOR USE IN ASSAYS THAT MEASURE TEST COMPOUND COMPETITIVE BINDING WITH SAM-UTILIZING PROTEINS | CAYMAN CHEMICAL COMPANY, INCORPORATED | 2015-11-12 | — | — | US | disclosed |
| US-9120820-B2 | Fluorescent molecular probes for use in assays that measure test compound competitive binding with SAM-utilizing proteins | CAYMAN CHEMICAL COMPANY, INCORPORATED (US) | 2015-09-01 | — | — | US | disclosed |
| US-20120295283-A1 | FLUORESCENT MOLECULAR PROBES FOR USE IN ASSAYS THAT MEASURE TEST COMPOUND COMPETITIVE BINDING WITH SAM-UTILIZING PROTEINS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-11-22 | — | — | US | disclosed |
| WO-2012159072-A2 | FLUORESCENT MOLECULAR PROBES FOR USE IN ASSAYS THAT MEASURE TEST COMPOUND COMPETITIVE BINDING WITH SAM-UTILIZING PROTEINS | CAYMAN CHEMICAL COMPANY, INCORPORATED (US) | 2012-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322107-A1 | FLUORESCENT MOLECULAR PROBES FOR USE IN ASSAYS THAT MEASURE TEST COMPOUND COMPETITIVE BINDING WITH SAM-UTILIZING PROTEINS | SAMSN1, TIPARP, SPR | CDK1 3386/4885ADORA1 1863/4885ADORA2A 1411/4885 |
| US-20150323542-A1 | FLUORESCENT MOLECULAR PROBES FOR USE IN ASSAYS THAT MEASURE TEST COMPOUND COMPETITIVE BINDING WITH SAM-UTILIZING PROTEINS | SAMSN1, TIPARP, SPR | CDK1 3386/4885ADORA1 1863/4885ADORA2A 1411/4885 |
| US-20120295283-A1 | FLUORESCENT MOLECULAR PROBES FOR USE IN ASSAYS THAT MEASURE TEST COMPOUND COMPETITIVE BINDING WITH SAM-UTILIZING PROTEINS | SAMSN1, TIPARP, SPR | CDK1 3386/4885ADORA1 1863/4885ADORA2A 1411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.