Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 4/20 | 0.52 |
| ▸ | CDK2 | P24941 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 4/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PNP | P00491 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16146951 | 0.84 | ADORA2A (0.41) | CDK1CDK2ALDH1A1 | |
| SCHEMBL15185178 | 0.83 | CDK1 (0.39) | CDK1CDK2 | |
| SCHEMBL10047091 | 0.82 | CDK1 (0.33) | CDK1CDK2 | |
| SCHEMBL1146235 | 0.82 | ADORA2A (0.44) | CDK1CDK2CYP3A4SLC29A1 | |
| SCHEMBL13836023 | 0.81 | CDK1 (0.39) | CDK1CDK2KMT2A | |
| SCHEMBL10047120 | 0.81 | L3MBTL1 (0.38) | CDK1CDK2KMT2AMEN1GAA | |
| SCHEMBL24207973 | 0.81 | KCNH3 (0.41) | CDK1CDK2KMT2A | |
| SCHEMBL16147159 | 0.81 | CDK1 (0.39) | CDK1CDK2CCNA2CCNA1CCNB1 | |
| SCHEMBL16146635 | 0.80 | XDH (0.42) | CDK1CDK2KMT2A | |
| SCHEMBL23133115 | 0.79 | CDK1 (0.43) | CDK1CDK2CCNA2CCNA1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000033657-A1 | METHOD TO IDENTIFY REGULATORS OF CDK ACTIVITY | CROPDESIGN N.V. (BE) | 2000-06-15 | — | — | WO | disclosed |