Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.81 |
| ▸ | MAPT | P10636 | 10/20 | 0.81 |
| ▸ | HTT | P42858 | 10/20 | 0.81 |
| ▸ | MEN1 | O00255 | 9/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.81 |
| ▸ | LMNA | P02545 | 9/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.81 |
| ▸ | CCR6 | P51684 | 2/20 | 0.81 |
| ▸ | RECQL | P46063 | 1/20 | 0.81 |
| ▸ | ALOX12 | P18054 | 7/20 | 0.80 |
| ▸ | POLB | P06746 | 1/20 | 0.80 |
| ▸ | BLM | P54132 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | ADAMTS5 | Q9UNA0 | 6/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30868633 | 0.91 | KMT2A (0.80) | KDM4EKMT2AMAPTHTTMEN1 | |
| SCHEMBL31533580 | 0.91 | KDM4E (0.67) | KDM4EKMT2AMAPTHTTMEN1 | |
| SCHEMBL2153199 | 0.90 | KDM4E (0.87) | KDM4EKMT2AMAPTHTTMEN1 | |
| SCHEMBL2153850 | 0.89 | MAPT (1.00) | KDM4EKMT2AMAPTHTTMEN1 | |
| SCHEMBL13836483 | 0.89 | HTT (0.75) | KDM4EKMT2AMAPTHTTMEN1 | |
| SCHEMBL13310332 | 0.89 | KDM4E (0.81) | KDM4EKMT2AMAPTHTTMEN1 | |
| SCHEMBL2153325 | 0.89 | MEN1 (0.84) | KDM4EKMT2AMAPTHTTMEN1 | |
| SCHEMBL31533567 | 0.88 | KDM4E (0.64) | KDM4EKMT2AMAPTHTTMEN1 | |
| SCHEMBL31533558 | 0.88 | LMNA (0.69) | KDM4EKMT2AMAPTHTTMEN1 | |
| SCHEMBL31672843 | 0.87 | KDM4E (0.63) | KDM4EKMT2AMAPTHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260103444-A1 | 8-HYDROXYQUINOLINE COMPOUND AND USE THEREOF | UNIV OSAKA (JP) | 2026-04-16 | — | — | US | disclosed |
| EP-4599832-A1 | 8-HYDROXYQUINOLINE COMPOUND AND USE THEREOF | OSAKA UNIVERSITY (JP) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024075815-A1 | 8-HYDROXYQUINOLINE COMPOUND AND USE THEREOF | 国立大学法人大阪大学 | 2024-04-11 | — | — | WO | disclosed |
| US-20120295890-A1 | GLYCOSAMINOGLYCAN INHIBITORS | Zacharon Pharmaceutical, Inc. (US) | 2012-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295890-A1 | GLYCOSAMINOGLYCAN INHIBITORS | CSGALNACT1, FUT5, ST3GAL3 | KDM4E 4113/4885KMT2A 4294/4885MAPT 4328/4885 |
| US-20260103444-A1 | 8-HYDROXYQUINOLINE COMPOUND AND USE THEREOF | MYLK2, MYLK, ATP2A1 | KDM4E 2263/4885KMT2A 1971/4885MAPT 4694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.