Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768124 | 0.88 | GPR119 (0.43) | GPR119 | |
| SCHEMBL1768146 | 0.87 | GPR119 (0.49) | GPR119 | |
| SCHEMBL1768189 | 0.87 | GPR119 (0.59) | GPR119 | |
| SCHEMBL12649728 | 0.86 | PIK3CD (0.41) | GPR119PIK3CD | |
| SCHEMBL13836355 | 0.86 | PIK3CD (0.41) | GPR119PIK3CD | |
| SCHEMBL1768120 | 0.86 | PIK3CD (0.41) | GPR119PIK3CD | |
| SCHEMBL12236496 | 0.79 | PIK3CD (0.52) | GPR119PIK3CD | |
| SCHEMBL20375465 | 0.78 | GPR119 (0.53) | GPR119PIK3CD | |
| SCHEMBL12259053 | 0.77 | GPR119 (0.55) | GPR119PIK3CD | |
| SCHEMBL1065920 | 0.77 | GPR119 (0.55) | GPR119PIK3CDNPBWR1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120295845-A1 | IMIDAZO-PYRAZOLES AS GPR119 INHIBITORS | PFIZER INC | 2012-11-22 | — | — | US | disclosed |
| US-20120295845-A1 | IMIDAZO-PYRAZOLES AS GPR119 INHIBITORS | PFIZER INC | 2012-11-22 | — | — | US | disclosed |
| US-20120295845-A1 | IMIDAZO-PYRAZOLES AS GPR119 INHIBITORS | PFIZER INC | 2012-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295845-A1 | IMIDAZO-PYRAZOLES AS GPR119 INHIBITORS | GPR3, GPR119, GPR84 | GPR119 2/4885PIK3CD 2596/4885NPBWR1 131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.