SCHEMBL13837233

SCHEMBL13837233

CCCCCCCCCCCCCCCCCCOc1cc(COc2cc(C(=O)O)cc(OCc3cc(OCCCCCCCCCCCCCCCCCC)c(OCCCCCCCCCCCCCCCCCC)c(OCCCCCCCCCCCCCCCCCC)c3)c2OCc2cc(OCCCCCCCCCCCCCCCCCC)c(OCCCCCCCCCCCCCCCCCC)c(OCCCCCCCCCCCCCCCCCC)c2)cc(OCCCCCCCCCCCCCCCCCC)c1OCCCCCCCCCCCCCCCCCC

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 1/20 0.55
ALDH1A1 P00352 1/20 0.49
HPGD P15428 1/20 0.49
PTPN11 Q06124 2/20 0.48
TP53 P04637 1/20 0.48
TSHR P16473 1/20 0.48
PLA2G4B P0C869 1/20 0.47
THRA P10827 1/20 0.46
THRB P10828 1/20 0.46
PLA2G2D Q9UNK4 1/20 0.45
RARB P10826 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14085628 0.90 PLA2G2A (0.66) PLA2G2AALDH1A1HPGDPTPN11TP53
SCHEMBL1200763 0.90 PLA2G2A (0.66) PLA2G2AALDH1A1HPGDPTPN11TP53
SCHEMBL1200970 0.90 PLA2G2A (0.66) PLA2G2AALDH1A1HPGDPTPN11TP53
SCHEMBL1201453 0.90 PLA2G2A (0.66) PLA2G2AALDH1A1HPGDPTPN11TP53
SCHEMBL1201538 0.90 PLA2G2A (0.66) PLA2G2AALDH1A1HPGDPTPN11TP53
SCHEMBL318045 0.90 PLA2G2A (0.66) PLA2G2AALDH1A1HPGDPTPN11TP53
SCHEMBL1108059 0.90 PLA2G2A (0.66) PLA2G2AALDH1A1HPGDPTPN11TP53
SCHEMBL1108057 0.90 PLA2G2A (0.66) PLA2G2AALDH1A1HPGDPTPN11TP53
SCHEMBL1200906 0.90 PLA2G2A (0.66) PLA2G2AALDH1A1HPGDPTPN11TP53
SCHEMBL28765484 0.90 PLA2G2A (0.66) PLA2G2AALDH1A1HPGDPTPN11TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2711370-B1 METHOD FOR PRODUCING OLIGONUCLEOTIDES AJINOMOTO KK (JP) 2018-01-03 EP disclosed
US-9029528-B2 Solution-based method of making oligonucleotides via phosphoramidite coupling AJINOMOTO CO., INC. (JP) 2015-05-12 US disclosed
EP-2711370-A1 METHOD FOR PRODUCING OLIGONUCLEOTIDE Ajinomoto Co., Inc. (JP) 2014-03-26 EP disclosed
US-20120296074-A1 PRODUCTION METHOD OF OLIGONUCLEOTIDE AJINOMOTO CO., INC. (JP) 2012-11-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120296074-A1 PRODUCTION METHOD OF OLIGONUCLEOTIDE RNGTT, POLM, RNMT PLA2G2A 3934/4885ALDH1A1 4056/4885HPGD 2764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.