Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.68 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12856364 | 1.00 | GABRA1 (0.68) | GABRA1GABRB2ALDH1A1TRPA1KDM4E | |
| SCHEMBL263474 | 0.92 | GABRA1 (0.73) | GABRA1GABRB2ALDH1A1TRPA1KDM4E | |
| SCHEMBL31229333 | 0.92 | GABRA1 (0.73) | GABRA1GABRB2ALDH1A1TRPA1KDM4E | |
| SCHEMBL17666370 | 0.92 | ALDH1A1 (0.59) | GABRA1GABRB2ALDH1A1TRPA1KDM4E | |
| SCHEMBL9824952 | 0.90 | GABRA1 (0.77) | GABRA1GABRB2ALDH1A1TRPA1KDM4E | |
| SCHEMBL921881 | 0.89 | GABRA1 (0.85) | GABRA1GABRB2 | |
| SCHEMBL68936 | 0.89 | ALDH1A1 (0.62) | GABRA1GABRB2ALDH1A1TRPA1KDM4E | |
| SCHEMBL15979586 | 0.89 | GABRA1 (0.59) | GABRA1GABRB2ALDH1A1TRPA1KDM4E | |
| SCHEMBL18462974 | 0.84 | ALDH1A1 (0.50) | GABRA1GABRB2ALDH1A1TRPA1KDM4E | |
| SCHEMBL11126429 | 0.83 | ALDH1A1 (0.54) | GABRA1GABRB2ALDH1A1TRPA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8716343-B2 | Calixarene-based peptide conformation mimetics, methods of use, and methods of making | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2014-05-06 | — | — | US | disclosed |
| US-8642656-B2 | Calixarene-based peptide conformation mimetics, methods of use, and methods of making | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2014-02-04 | — | — | US | disclosed |
| US-20130035394-A1 | Calixarene-Based Peptide Conformation Mimetics, Methods of Use, and Methods of Making | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2013-02-07 | — | — | US | disclosed |
| US-20120309801-A1 | CALIXARENE-BASED PEPTIDE CONFORMATION MIMETICS, METHODS OF USE, AND METHODS OF MAKING | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2012-12-06 | — | — | US | disclosed |
| US-7537974-B2 | Photoresist composition, method for forming film pattern using the same, and method for manufacturing thin film transistor array panel using the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2009-05-26 | — | — | US | disclosed |
| US-20070154837-A1 | Composition for hard mask and method for manufacturing semiconductor device | HYNIX SEMICONDUCTOR INC. (KR) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130035394-A1 | Calixarene-Based Peptide Conformation Mimetics, Methods of Use, and Methods of Making | CLSPN, BID, CALU | GABRA1 2616/4885GABRB2 2538/4885ALDH1A1 4794/4885 |
| US-20120309801-A1 | CALIXARENE-BASED PEPTIDE CONFORMATION MIMETICS, METHODS OF USE, AND METHODS OF MAKING | CLSPN, BID, CALU | GABRA1 2616/4885GABRB2 2538/4885ALDH1A1 4794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.