SCHEMBL9824952

SCHEMBL9824952

CCc1cccc(CC)c1O.Cc1cccc(C)c1O

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.77
GABRB2 P47870 4/20 0.77
ALDH1A1 P00352 2/20 0.64
TRPA1 O75762 2/20 0.50
KDM4E B2RXH2 1/20 0.47
HPGD P15428 1/20 0.47
HSD17B10 Q99714 1/20 0.47
ATM Q13315 1/20 0.44
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
POLB P06746 1/20 0.41
SHBG P04278 1/20 0.41
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
PTGS2 P35354 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL263474 0.93 GABRA1 (0.73) GABRA1GABRB2ALDH1A1TRPA1KDM4E
SCHEMBL31229333 0.93 GABRA1 (0.73) GABRA1GABRB2ALDH1A1TRPA1KDM4E
SCHEMBL12856364 0.90 GABRA1 (0.68) GABRA1GABRB2ALDH1A1TRPA1KDM4E
SCHEMBL13839296 0.90 GABRA1 (0.68) GABRA1GABRB2ALDH1A1TRPA1KDM4E
SCHEMBL199730 0.88 GABRA1 (1.00) GABRA1GABRB2CA2ESR1ESR2
Water SCHEMBL28947715 0.83 GABRA1 (0.90) GABRA1GABRB2ALDH1A1
Alcohol SCHEMBL28268569 0.83 GABRA1 (0.90) GABRA1GABRB2ALDH1A1PTGS2
SCHEMBL15979586 0.83 GABRA1 (0.59) GABRA1GABRB2ALDH1A1TRPA1KDM4E
Propane SCHEMBL11575912 0.83 ALDH1A1 (0.82) GABRA1GABRB2ALDH1A1TRPA1KDM4E
Propane SCHEMBL27536178 0.83 ALDH1A1 (0.82) GABRA1GABRB2ALDH1A1TRPA1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0259746-B1 PROCESS FOR PRODUCING 2,2-BIS(4'-HYDROXYPHENYL) PROPANES IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1991-05-15 EP disclosed
US-4814520-A CONDENSATION OF UNSATURATED COMPOUND AND PHENOL IDEMITSU PETROCHEMICAL COMPANY LIMITED (JP) 1989-03-21 US disclosed
EP-0259746-A1 Process for producing 2,2-bis(4'-hydroxyphenyl) propanes IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1988-03-16 EP disclosed