⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13650036 | 0.93 | LMNA (0.30) | — | |
| SCHEMBL13650025 | 0.84 | ALDH1A1 (0.33) | — | |
| SCHEMBL13725076 | 0.81 | LMNA (0.33) | — | |
| SCHEMBL13650028 | 0.80 | — | — | |
| SCHEMBL13726434 | 0.80 | — | — | |
| SCHEMBL13839391 | 0.79 | — | — | |
| SCHEMBL13725452 | 0.79 | — | — | |
| SCHEMBL14081712 | 0.79 | ADK (0.35) | — | |
| SCHEMBL4014575 | 0.79 | ADK (0.35) | — | |
| SCHEMBL13870386 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534771-B2 | Tricyclic-nucleoside prodrugs for treating viral infections | SMITHKLINE BEECHAM CORPORATION (US) | 2009-05-19 | — | — | US | disclosed |