Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 5/20 | 0.55 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383944 | 1.00 | OXTR (0.55) | OXTRAVPR1AMAPTALDH1A1FKBP1A | |
| SCHEMBL4430007 | 1.00 | OXTR (0.55) | OXTRAVPR1AMAPTALDH1A1FKBP1A | |
| SCHEMBL4422768 | 0.92 | OXTR (0.57) | OXTRAVPR1AMAPTALDH1A1KMT2A | |
| SCHEMBL4422772 | 0.92 | OXTR (0.57) | OXTRAVPR1AMAPTALDH1A1KMT2A | |
| SCHEMBL13789768 | 0.85 | OXTR (0.63) | OXTRAVPR1AMAPTALDH1A1KMT2A | |
| SCHEMBL8319369 | 0.85 | OXTR (0.63) | OXTRAVPR1AMAPTALDH1A1KMT2A | |
| SCHEMBL4418288 | 0.85 | OXTR (0.63) | OXTRAVPR1AMAPTALDH1A1KMT2A | |
| SCHEMBL4418290 | 0.85 | OXTR (0.63) | OXTRAVPR1AMAPTALDH1A1KMT2A | |
| SCHEMBL4416737 | 0.84 | MAPT (0.48) | MAPTALDH1A1FKBP1AKMT2AMEN1 | |
| SCHEMBL4416740 | 0.84 | MAPT (0.48) | MAPTALDH1A1FKBP1AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4773335-B2 | — | — | 2011-09-14 | — | — | JP | claimed |
| EP-1597229-A2 | PYRROLIDINE DERIVATIVES AS OXYTOCIN ANTAGONISTS | Applied Research Systems ARS Holding N.V. (AN) | 2005-11-23 | — | — | EP | claimed |
| WO-2004076407-A2 | PYRROLIDINE DERIVATIVES AS OXYTOCIN ANTAGONISTS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2004-09-10 | — | — | WO | claimed |