Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4416737 | 1.00 | MAPT (0.48) | MAPTALDH1A1FKBP1AFAAHMGLL | |
| SCHEMBL4419585 | 0.90 | MAPT (0.51) | MAPTALDH1A1FKBP1AFAAHMGLL | |
| SCHEMBL4419582 | 0.90 | MAPT (0.51) | MAPTALDH1A1FKBP1AFAAHMGLL | |
| SCHEMBL1383944 | 0.84 | OXTR (0.55) | MAPTALDH1A1FKBP1AFAAHMGLL | |
| SCHEMBL1383941 | 0.84 | OXTR (0.55) | MAPTALDH1A1FKBP1AFAAHMGLL | |
| SCHEMBL4430007 | 0.84 | OXTR (0.55) | MAPTALDH1A1FKBP1AFAAHMGLL | |
| SCHEMBL4422773 | 0.83 | SMN1; SMN2 (0.43) | TSHRHPGDSMN1; SMN2RAB9APOLB | |
| SCHEMBL13789901 | 0.83 | SMN1; SMN2 (0.43) | TSHRHPGDSMN1; SMN2RAB9APOLB | |
| SCHEMBL4414514 | 0.80 | HPGD (0.42) | TSHRHPGDSMN1; SMN2RAB9APOLB | |
| SCHEMBL4414519 | 0.80 | HPGD (0.42) | TSHRHPGDSMN1; SMN2RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597229-B1 | PYRROLIDINE DERIVATIVES AS OXYTOCIN ANTAGONISTS | MERCK SERONO SA (CH) | 2009-11-18 | — | — | EP | claimed |
| EP-1597229-B1 | PYRROLIDINE DERIVATIVES AS OXYTOCIN ANTAGONISTS | MERCK SERONO SA (CH) | 2009-11-18 | — | — | EP | disclosed |